This content is machine translated Malignant melanoma of the skin Current European Guideline at a glance Malignant melanoma of the skin has a high metastatic rate and accounts for more than 90% of all skin cancer-related deaths. Therefore, early detection and best possible treatment is very…
View Post 4 min This content is machine translated Epidermolysis bullosa Wound chronicity and tumorigenesis – relevance of T cell-mediated mechanisms. Bullous autoimmune dermatoses result from an autoantibody-driven immune response against structural proteins of the skin. Chronic wounds in the setting of recessively inherited dystrophic epidermolysis bullosa (RDEB) are highly susceptible…
View Post 4 min This content is machine translated System therapy for atopic dermatitis: biologics or JAK inhibitors? Balancing benefits and risks The era of targeted systemic treatment began several years ago and the therapy armamentarium is constantly expanding, so that the question of selection criteria for the individually appropriate therapy is…
View Post 5 min This content is machine translated Systemic mastocytosis Diagnostics and drug therapy approaches – an update A KIT mutation analysis from the bone marrow is recommended in the case of highly elevated tryptase levels. In particular, adults often have a point mutation in codon 816 of…
View Post 8 min This content is machine translated Psoriasis The era of biologics – a tour d’horizon through significant research decades The development of highly effective biologics was preceded by research efforts over several decades. Advances in immunopathogenetic and molecular genetic analyses contributed significantly to the generation of these innovative system…
View Post 10 min This content is machine translated Disease of the subcutaneous adipose tissue Lipedema – a painful fatty tissue disease of the extremities in women. Lipedema is a painful, disproportionate increase in fat in women; on legs and arms, as well as hips and buttocks. Lipedema has been officially classified as a disease in the… CME-Test
View Post 3 min This content is machine translated Rare diseases Current diagnostic criteria for neurofibromatosis type 1 – an update. Also known as “von Recklinghausen disease,” neurofibromatosis type 1 is a rare genetic multi-organ disease. A common feature of neurofibromatosis type 1 that can be diagnosed early in its course…
View Post 2 min This content is machine translated Atopic dermatitis in childhood and adolescence Dupilumab proves itself in daily practice In the “BioDay Registry” study, treatment with dupilumab in pediatric patients with atopic dermatitis in a “real world” setting resulted in significant improvement in disease severity and associated symptoms. Tolerability…
View Post 8 min This content is machine translated Ichthyoses Broad spectrum of genetic cornification disorders Ichthyoses comprise a heterogeneous group of rare hereditary skin disorders whose classification can prove difficult. Accordingly, rapid diagnosis and therapy initiation is a challenge in everyday clinical practice. Experts specialized…
View Post 6 min This content is machine translated Clarification of contact eczema Important and common allergens – an up-to-date overview Frequently, chronic contact dermatitis is a combination of irritant and contact allergic eczema. The selection of the test allergens is anamnesis-guided. In addition to nickel – still the most common… CME-Test
View Post 3 min This content is machine translated Cutaneous T-cell lymphoma (CTCL) First targeted antibody approved for CTCL patients with MF or SS The approval of the anti-CCR4 antibody mogamulizumab provides patients with cutaneous T-cell lymphoma (CTCL) of the mycosis fungoides (MF) and Sézary syndrome (SS) subtypes with an effective non-chemotherapeutic intervention for…
