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Dermatology and venereology

1025 posts
  • This content is machine translated Geriatric dermatology: study report.

Skin cancer as a leading diagnosis in elderly hospitalized dermatologic patients

In view of the demographic development, the importance of skin diseases in geriatric patients is increasing in everyday practice. A study by a German research team analyzed data from patients…
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  • 7 min
  • This content is machine translated Dermatomyositis

Diagnostics and treatment – a current overview

Pathognomonic skin signs of dermatomyositis include heliotrope erythema, Gottron papules, and Gottron signs. The determination of myositis-specific autoantibodies has an increasingly important role in the diagnosis. Regarding treatment options, intravenous…
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  • 3 min
  • This content is machine translated Plaque psoriasis

TYK2 inhibition shows great therapeutic potential

Psoriasis is nowadays understood as a systemic disease, which is based on chronic inflammation. Research into the etiopathogenesis, as well as the establishment of new active substances, is progressing rapidly.…
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  • 4 min
  • This content is machine translated Biologics for atopic dermatitis

Symptom relief through targeted inhibition of inflammatory signaling pathways

Monoclonal antibodies are systems therapeutics that block specific cytokines or receptors and can thus selectively influence individual activation cascades of the immune system. Both dupilumab and tralokinmab – the two…
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  • 3 min
  • This content is machine translated Atopic dermatitis

Multifactorial etiology with dysregulation of type 2 cytokines.

Genetic predisposition, an impaired epidermal barrier with altered microbiome, and aberrant immune responses with type 2 inflammation are associated with the occurrence and activity of atopic dermatitis. Various provoking factors…
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  • 5 min
  • This content is machine translated The difficult acne patient

Systemic retinoid therapy – informing about opportunities and risks

Oral isotretinoin can be very effective in treating severe forms of acne that do not respond sufficiently to topical and systemic antibiotic therapy. In advance, patients should be informed about…
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  • 2 min
  • This content is machine translated Rare skin diseases

Clouston syndrome – a hidrotic ectodermal dysplasia.

Clouston syndrome is an autosomal dominant inherited disorder characterized by the leading symptoms of hyperkeratosis, nail dystrophy and alopecia. The syndrome is caused by mutations in the GJB6 gene, which…
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  • 6 min
  • This content is machine translated Treatment of varicose veins

Endovenous laser ablation – an update

Varicose veins can be effectively treated using endovenous laser ablation (EVLA). The effectiveness of EVLA depends not only on the laser energy density in the vein but also on the…
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  • 5 min
  • This content is machine translated Wound Management

Detect, understand and sustainably eliminate biofilm

If biofilm colonization persists in chronic wounds despite the best possible treatment of the underlying disease, this causes wound healing to stagnate. Mechanical debridement is extremely important, but is not…
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  • 6 min
  • This content is machine translated Alopecia areata: drug therapy

Which method achieves the best hair growth rates?

Alopecia areata (AA) manifests as acute or chronic non-scarring hair loss. Diphenylcyclopropenone and Janus kinase inhibitors have a significantly higher remission rate compared with the spontaneous course, especially in severe…
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  • 3 min
  • This content is machine translated Alopecia areata: diagnostics

Nail involvement is associated with severe course

Typically, alopecia areata (AA) presents with sharply demarcated round foci. Trichoscopy can provide valuable information; scalp biopsy is indicated only in exceptional cases. The course of AA varies greatly from…

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