This content is machine translated Rare diseases The Alagille syndrome This rare genetic disorder is associated with multiple symptoms of multiple organ systems, particularly affecting the liver and heart. The cause is a mutation on chromosome 1 or 20. The…
View Post 7 min This content is machine translated Atopic dermatitis: choice of systemic therapy option “It’s always an individual weighing”. For the treatment of moderate and severe atopic dermatitis, three oral Janus kinase inhibitors are now available in addition to two subcutaneously administered biologics. While the former specifically target individual…
View Post 6 min This content is machine translated Generalized Pustular Psoriasis (GPP) What is currently known about this rare systemic disease? Macroscopically visible sterile, confluent pustules on non-acral skin and extensive erythema and edema are among the characteristic manifestations of generalized pustular psoriasis – a severe inflammatory, potentially life-threatening skin disease.…
View Post 5 min This content is machine translated Atopic dermatitis Achieving high treatment goals with the Minimal Disease Activity concept Patients with moderate to severe atopic dermatitis suffer from the physical and psychological effects of the disease and yet do not receive adequate treatment with systemic therapies, or often only…
View Post 3 min This content is machine translated Rare skin diseases Hyperkeratosis lenticularis perstans aka Flegel’s disease Flegel’s disease is a genodermatosis with manifestation in the second half of life. Topical topical preparations such as those containing urea or cortisone are currently used for therapy. To clarify…
View Post 12 min This content is machine translated Sustainability in dermatology Where do we stand, where do we want to go? The healthcare sector is particularly resource-intensive; a visit to a modern intensive care unit is enough to illustrate this. However, when considering the totality of practices, hospitals, treatments and associated… CME-Test
View Post 13 min This content is machine translated Platelet-rich plasma in theory and practice Regulatory guardrails in the manufacture of PRP and PRP combination therapies. Platelet-rich plasma” (PRP) has established itself as a useful option for autologous reinjection in the regenerative medicine of numerous specialties for the therapy of disturbed healing processes. Standardized manufacturing process… CME-Test
View Post 4 min This content is machine translated Malignant melanoma Improved prognosis in most common cancer at all stages Malignant melanoma is one of the most common malignant tumors, especially in adolescent age groups. However, given the state of knowledge on the proliferation and antigenicity pattern of tumor cells,…
View Post 4 min This content is machine translated Rare skin diseases Porokeratoses – chronic cornification disorder of the epidermis Clinically, porokeratoses are characterized by a keratinization disorder. Several porokeratosis variants are distinguished. A common histologic feature of all porokeratoses is corneal lamellae in the marginal ridge area. Due to…
View Post 7 min This content is machine translated Geriatric dermatology Chronic pruritus in the elderly Pruritus is a common problem in the elderly, which can occur not only in the context of dermatoses, but also as a secondary symptom of other diseases. Aging skin is…
View Post 4 min This content is machine translated Case Report Suspicion of monkeypox infection confirmed Patients with exanthema accompanied by nonspecific fever should also be considered for monkeypox infection. Especially in case of monomorphic change of skin florescences, re-diagnosis is advisable. Vaccination should be considered…