This content is machine translated Atherosclerotic Coronary Plaques in High-Risk Patients Who benefits from preventive PCI? For patients with ASCVD, modern imaging techniques such as CCTA and cardiac MRI often provide a solid basis for subsequent treatment decisions. The invasive cardiac catheterization procedure is currently used...…
View Post 5 min This content is machine translated Colorectal Cancer Insulin Resistance, Obesity, and Progression Colorectal cancer is one of the most common malignant tumors worldwide and is increasingly linked to metabolic disorders such as insulin resistance and obesity. New epidemiological data show significant shifts...…
View Post 12 min This content is machine translated Hepatology and Metabolism The Mediterranean Diet for MASLD/MASH—What the EASL-EASD-EASO Guidelines Specifically Recommend Since an international Delphi consensus in 2023, the condition formerly known as nonalcoholic fatty liver disease (NAFLD) has been called MASLD— “metabolic dysfunction-associated steatotic liver disease.” It is defined as...…
View Post 18 min This content is machine translated From an antidiabetic drug to a distinct class of cardiorenal therapies The Incretin Revolution in Cardiology Within a decade, incretin mimetics have evolved from blood-sugar-lowering diabetes medications into one of the most dynamic classes of drugs in cardiovascular medicine. GLP-1 receptor agonists (GLP-1-RA) have been shown...…
View Post 12 min This content is machine translated Cardiology and Nutrition Ultra-Processed Foods and Cardiovascular Risk—The New AHA Position Ultra-processed foods (UPFs ) account for a significant portion of energy intake in Western countries—in the United States, an estimated more than half. Given this ubiquity and a growing number...…
View Post 7 min This content is machine translated Obesity: A Multimodal and Interdisciplinary Approach New Swiss Clinical Practice Guideline Provides Guidance The guidelines developed by Swiss professional associations (Swiss Obesity Clinical Practice Guidance) contain evidence-based recommendations for the diagnosis and treatment of obesity, with a focus on improving health, quality of...…
View Post 6 min This content is machine translated Advanced Thyroid Cancer Molecular Mechanisms and New Therapeutic Approaches Thyroid carcinomas exhibit remarkable biological heterogeneity, which is increasingly shaping modern diagnosis and treatment. Molecular markers and innovative treatment approaches are fundamentally changing our understanding of pathogenesis, prognosis, and clinical...…
View Post 18 min This content is machine translated From Risk Identification to Anti-Inflammatory Intervention Inflammation as a Treatment Goal in Its Own Right For decades, cardiovascular prevention was essentially a story about cholesterol. Yet a significant proportion of patients experience adverse events despite optimally controlled lipid levels—a reflection of a residual risk that...… CME-Test
View Post 11 min This content is machine translated Cardiometabolism Retatrutid and the TRIUMPH Program: The Triple Agonist on the Horizon Incretin-based obesity therapy has advanced rapidly in just a few years: from GLP-1 receptor agonists (semaglutide) to the dual GIP/GLP-1 agonist tirzepatide and on to a triple agonist. Retatrutide (LY3437943)...…
View Post 4 min This content is machine translated MASH Pharmacotherapies as “Game Changers”—What Are the Upcoming Challenges? Two drug therapy options—semaglutide (s.c.) and resmetirom (oral)—are now approved in the EU and the U.S. for the treatment of MASH. This is a major breakthrough, especially since, for a...…
View Post 13 min This content is machine translated Obesity Treatment Oral GLP-1 Therapies: ATTAIN-1 and OASIS-4—The Next Leap Forward Injectable GLP-1 receptor agonists and the dual GIP/GLP-1 agonist tirzepatide have redefined pharmacological obesity treatment and achieved weight loss in the range of 15 to 20% in clinical trials. Nevertheless,...…
