This content is machine translated SCORE2 diabetes 10-year estimate of cardiovascular risk in type 2 diabetes. To develop and validate a recalibrated prediction model (SCORE2-Diabetes) to estimate the 10-year risk of cardiovascular disease in individuals aged over 40 years with type 2 diabetes in four different…
View Post 5 min This content is machine translated Obesity GLP-1 analogs and dual incretin agonists to support weight loss. Pathological obesity is a key risk factor for the development of life-threatening secondary complications. Until recently, bariatric surgery was the only effective method for obesity sufferers to achieve a sustained…
View Post 5 min This content is machine translated Heart failure in type 2 diabetes Success story of SGLT-2 inhibitors – impressive evidence base. The SGLT(“sodium glucose-linked transporter”)-2 inhibitors have demonstrated cardioprotective effects in addition to antidiabetic effects. The current evidence supports the benefit of several agents of SGLT-2-i in the treatment of heart…
View Post 3 min This content is machine translated GLP-1-RA and dual GLP-1/GIP agonists. Tackling obesity – not only diabetics benefit from the effects While glucagon-like peptide (GLP)-1 receptor agonists have been successfully used in the treatment of diabetes for some time, there are now agents that activate not only the GLP-1 receptor but…
View Post 2 min This content is machine translated Polyneuropathies Optimal treatment of peripheral nerve diseases Polyneuropathies are generalized disorders of the peripheral nervous system and, with a prevalence of 5-8%, are most common in patients with chronic alcohol abuse, diabetes, or malignancies. In addition to…
View Post 6 min This content is machine translated Patient-adapted diabetes therapy “Time in Range” and AID systems gain in importance Both continuous glucose monitoring (CGM) systems and sensor-assisted insulin therapy are already widely available. Devices for automated insulin delivery (AID) such as hybrid or closed loop AID will play an…
View Post 4 min This content is machine translated Hypothyroidism L-thyroxine monotherapy is still considered the standard of care Patients with elevated TSH values should be evaluated for possible hypothyroidism, taking into account the respective reference standard value ranges and intra- and interindividual variability. In patients with hypothyroidism requiring…
View Post 9 min This content is machine translated Type 2 diabetes Updated SGED treatment recommendations published In recent years, the therapeutic landscape for type 2 diabetes has changed significantly. Because GLP-1 receptor agonists and SGLT-2 inhibitors have shown direct effects on cardiorenal protection in cardiovascular endpoint…
View Post 3 min This content is machine translated Thyroid nodule New risk assessment shows lower malignancy rate than previously thought Nodes on the thyroid gland are very common. In the vast majority, thyroid nodules are benign. This is also confirmed by the results of a recent long-term German study, according…
View Post 5 min This content is machine translated Chronic renal failure in type 2 diabetes Using nephroprotective therapy options and slowing progression In type 2 diabetics, renal function should be checked at regular intervals. Nowadays, modern treatment approaches are available that can slow down the progression of diabetic nephropathy. If early use…
View Post 4 min This content is machine translated Chronic pancreatitis Exocrine insufficiency is treatable by enzyme replacement therapy Inflammation-induced connective tissue remodeling of the pancreas leads to progressive loss of exocrine and endocrine gland function. For the treatment of exocrine insufficiency – which usually manifests itself late in…
