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Gastroenterology and Hepatology

447 posts
  • This content is machine translated Rare diseases

Gaucher disease – a sphingolipidosis

A young adult patient with abdominal pain was found to have hepatomegaly and splenomegaly associated with thrombocytopenia and anemia. The bone marrow was then punctured and biopsied, followed by determination…
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  • 3 min
  • This content is machine translated Mucosal injury

Colitis due to sevelamer crystals

Sevelamer is a widely used non-calcium-based phosphate-binding agent used to lower serum phosphate levels in chronic kidney disease (CKD) and end-stage renal disease ( ESRD). As a rule, it is…
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  • 4 min
  • This content is machine translated Post-pancreatitis diabetes

Insulin requirement three times as high as for type 2

Post-pancreatitis diabetes mellitus ( PPDM) is a common consequence of chronic pancreatitis (CP). However, patients with PPDM are often misclassified as type 2 diabetics. However, clinically significant complications may be…
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  • 3 min
  • This content is machine translated Hereditary angioedema

New Real-World Data on Long-Term Prophylaxis

Hereditary angioedema (HAE) is a rare genetic disorder that causes recurrent swelling of the skin, mucous membranes, or various internal organs at irregular intervals. International guidelines recommend long-term prophylaxis with…
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  • 3 min
  • This content is machine translated Fatty liver disease

New widespread disease NAFLD

Model calculations suggest that the number of patients with cirrhosis, advanced fibrosis, or hepatocellular carcinoma (HCC) could double to triple in the next 10-15 years. Not least because of this,…
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  • 4 min
  • This content is machine translated Irritable Bowel Syndrome

Align therapy with the predominant symptom

Irritable bowel syndrome (IBS) manifests as a heterogeneous clinical picture in terms of the type and severity of symptoms, affecting around 16% of the population. Diagnostically, IBS is a challenge…
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  • 11 min
  • This content is machine translated H. pylori and gastroduodenal ulcer disease.

Helicobacter pylori – what’s new in practice?

Forty years have passed since the landmark publication on the importance of Helicobacter pylori as a triggering factor for gastritis by Warren and Marshall. In that time, the understanding of…
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  • 5 min
  • This content is machine translated Menthacarin for functional digestive disorders

New secondary analysis confirms effective symptom relief

Functional gastrointestinal disorders are defined by Rome-IV as disorders of gut-brain interaction. Dyspeptic symptoms are often accompanied by typical irritable bowel symptoms, such as irregular bowel movements and flatulence. A…
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  • 4 min
  • This content is machine translated Gastrointestinal tumors

Latest scientific findings from stomach to colon

Themed “Applying Innovation, Transforming Care, Advancing Equity,” ASCO-GI celebrated its 20th anniversary this year. The focus this year was primarily on current findings relating to gastric carcinoma. However, further studies…
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  • 5 min
  • This content is machine translated Non-alcoholic fatty liver disease (NAFLD)

What does the current guideline say?

Non-alcoholic fatty liver disease is the most common liver disease worldwide. The German S2k guideline, updated in 2022, recommends screening patients at risk. The proposed screening algorithm includes fibrosis assessment…
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  • 11 min
  • This content is machine translated IBD matters: Module four

Molecular mechanisms in pathogenesis and treatment.

Studies have shown that altered immune cell transport and pathogenic immune cells are critical factors responsible for mucosal inflammation and tissue destruction in IBD. A defective intestinal barrier and microbial…
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