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General Internal Medicine

1990 posts
  • This content is machine translated From symptom to diagnosis

Abdominal pain – Sprue

The term sprue is used for two different diseases that are associated with chronic diarrhea: tropical sprue and celiac disease (gluten-sensitive enteropathy), formerly known as indigenous sprue [1]. This is...…
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  • 8 min
  • This content is machine translated Benefits, limits and safety aspects

Phytotherapy for cardiovascular diseases

Herbal preparations and “natural” dietary supplements are frequently used by patients with cardiovascular disease – often in the hope of “gently” influencing blood pressure, lipids or symptoms. However, guidelines from...…
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  • 9 min
  • This content is machine translated Neuroprotection, resilience and cognitive health in old age

Longevity & Brain

Cognitive health in old age is not an inevitable fate, but can be influenced to a relevant extent by modifiable factors. The Lancet Commission 2024 concludes that a significant proportion...…
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  • 6 min
  • This content is machine translated Obesity as a chronic disease: an interdisciplinary perspective

Neurobiological mechanisms of obesity

A high-fat and high-sugar diet affects both the homeostatic hunger and satiety signals in the hypothalamus and the hedonic reward system, leading to persistent hunger and a strong craving for...…
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  • 3 min
  • This content is machine translated Phimosis and penile cancer under SGLT2i

Increased risk for men with T2D

In recent years, sodium-glucose cotransporter 2 inhibitors (SGLT2i) have been widely used in the treatment of type 2 diabetes, as they not only provide improved glycemic control, but also offer...…
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  • 4 min
  • This content is machine translated Therapy of non-tumor-related pain

Do not prescribe opioids lightly for musculoskeletal pain

A UK research team used electronic primary care patient records from 2006-2021 based on the Clinical Research Practice Datalink (CPRD) to identify opioid prescriptions. The analyses revealed that almost three...…
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  • 10 min
  • This content is machine translated A hub of biological aging

Mitochondrial dysfunction and energy metabolism

Mitochondrial dysfunction is not defined as an isolated “ATP problem” in the Hallmarks of Ageing framework, but as a systemic shift in bioenergetics, redox signaling, quality control and immune metabolism....…
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  • 3 min
  • This content is machine translated Health Literacy

Promoting health literacy: from the abstract to the concrete level

The Federal Council’s health policy strategy “Health 2030” sets out a framework for action in health policy aimed at securing healthcare provision in the coming years. The second of the...…
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  • 4 min
  • This content is machine translated Case study

Wiedemann-Steiner syndrome in a 2-year-old girl

The patient, who had a phenotype characterized by hypertelorism, thick eyebrows and other features, was found to have a c.517C>T nonsense mutation in the KMT2A gene. This rare heterozygous mutation...…
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  • 4 min
  • This content is machine translated Chronic back pain

Care in the virtual hospital – the Back@home project

As part of the Back@Home study, the effectiveness of a virtual hospital model is being evaluated in patients with musculoskeletal back pain who present to the emergency room. One of...…
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  • 5 min
  • This content is machine translated Study report: TBS v3 and v4 in comparison

Analysis of OsteoLaus study data

The OsteoLaus study is part of the prospective, population-based CoLaus/PsyColaus study of postmenopausal women in Switzerland. In an analysis published in Osteoporosis International in 2025, the Trabecular Bone Score (TBS)...…

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