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General Internal Medicine

1890 posts
  • This content is machine translated CKD: counteracting kidney progression and reducing the risk of CVD

Targeted intervention through a multifactorial approach

The Swiss Society of Nephrology (SGN) advocates targeted screening for defined risk groups. However, given the prevalence of chronic kidney disease (CKD) in primary care, it is hardly possible to...…
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  • 11 min
  • This content is machine translated COPD therapy

Drug therapy – Update 2025

Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory multisystem disease caused primarily by inhaled noxious substances in combination with environmental factors and genetic predispositions. The presence of such a...…
CME-Test
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  • 5 min
  • This content is machine translated Side effects under opioid therapy

Is it possible to avoid the inevitable?

Opioid analgesics are an essential tool for the relief of cancer-related pain. However, in addition to their undeniable therapeutic value, opioids are associated with a number of predictable side effects...…
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  • 9 min
  • This content is machine translated Diagnostics of respiratory viral infections

What is tested when and on whom?

The diagnosis of respiratory viral infections has become a major focus of medical attention in recent years. While SARS-CoV-2 has taken center stage in recent years, other respiratory viruses such...…
CME-Test
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  • 13 min
  • This content is machine translated Focus on prevention

Colorectal cancer screening – an update

Colorectal cancer is a relevant disease for society: every twentieth person in Switzerland is affected at least once in their lifetime. In Switzerland, around 4300 new cases occur every year...…
CME-Test
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  • 6 min
  • This content is machine translated Severe acute pancreatitis

COX-2 inhibition alleviates inflammation and improves outcomes

Severe acute pancreatitis represents a persistent therapeutic challenge due to its unpredictable course and the lack of targeted pharmacological options. Despite improved supportive care, mortality remains high, especially in cases...…
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  • 2 min
  • This content is machine translated Ulcerative colitis

Rgs14 protein can worsen the severity

Rgs14 is a protein that acts as a regulator of G-protein signaling pathways by accelerating the GTPase activity of G-protein alpha subunits and thereby converting them to their inactive GDP-bound...…
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  • 5 min
  • This content is machine translated Eosinophilic esophagitis

EoE rarely occurs in isolation

Eosinophilic oesophagitis (EoE) is still inadequately treated in terms of its association with other type 2 inflammatory diseases (T2). Italian researchers attempted to close this gap. Their conclusion: In EoE...…
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  • 3 min
  • This content is machine translated Ginkgo biloba extract in the Alzheimer's mouse model

Effects on disease-associated microglia subpopulations

During the progression of Alzheimer’s disease, microglial cells located in the vicinity of plaques become overactivated and release cytotoxic mediators such as TNFα. In an animal study published in 2025,...…
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  • 3 min
  • This content is machine translated "Patients W.A.I.T Indicator"

Access to medicines – how does Switzerland compare across Europe?

According to a major international study, Switzerland has once again fallen behind other European countries in terms of access to new innovative medicines – from sixth to seventh place. Particularly...…
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  • 4 min
  • This content is machine translated Crohn's disease and depression

Significant psychological stress for CD patients

Crohn’s disease (CD) is often associated with extraintestinal symptoms (EIM). However, the connection with mental disorders is also being increasingly emphasized. Spanish scientists analyzed the frequency and severity of depression...…

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