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General Internal Medicine

1988 posts
  • This content is machine translated Global Recommendation, Swissmedic Approval, and SL Limitation

WHO Guidelines on GLP-1 for Obesity

With the guideline published on December 1, 2025, the World Health Organization has, for the first time, issued a globally applicable recommendation on the pharmacological management of obesity in adults....…
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  • 7 min
  • This content is machine translated Obesity in Children and Adolescents

Gene-Environment Interactions: Polygenic or Monogenic Determinants?

In the context of precision medicine, a differentiated approach to the diagnosis of obesity provides an essential foundation for implementing improved strategies for prevention, treatment, and prognosis. Obesity is often...…
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  • 9 min
  • This content is machine translated Congenital Vascular Malformations

Personalized Treatment Before a Planned Pregnancy

Vascular malformations have a prevalence of 1% and an incidence of 3–5 per 10,000. Anomalies can affect any organ system in children and adults. Mosaic mutations occurring during embryonic development...…
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  • 7 min
  • This content is machine translated H. pylori infection: current study data

Fewer gastric carcinomas and peptic ulcers after eradication

Despite a worldwide decline in the prevalence of Helicobacter pylori (H. pylori), the infection is still widespread. It is estimated that around one in three people in Europe is colonized...…
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  • 4 min
  • This content is machine translated From symptom to diagnosis

Pneumology – tracheal and bronchial calcifications

Tracheal and bronchial calcifications are based on imaging findings that can indicate various underlying diseases. Those affected often suffer from a chronic cough. The diagnosis can be confirmed by X-ray...…
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  • 7 min
  • This content is machine translated Geriatric patients

Micronutrient Intake in Older Adults

Extrinsic and intrinsic factors contribute to older adults being less likely to meet the recommended daily intake of micronutrients. This can have significant negative health consequences. Micronutrients that are particularly...…
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  • 7 min
  • This content is machine translated Crohn's disease: focus on long-term results

“Top-down” approach or classic step therapy?

The standard treatment of Crohn’s disease (Crohn’s disease) is based on the “step-up” strategy. However, results from the PROFILE study indicate that in newly diagnosed Crohn’s disease, early use of...…
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  • 4 min
  • This content is machine translated SwissDiab Study: New Analysis Published

How are diabetes complications associated with quality of life?

The Swiss Diabetes Registry (SwissDiab) is a multicenter, national observational study and patient registry that collects data on complications in adults with diabetes mellitus in Switzerland. A recent analysis published...…
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  • 6 min
  • This content is machine translated Pre-acclimatization on Mount Everest

Exploring the physiological limits

Traditionally, a period of six to nine weeks is planned for an Everest expedition. This established practice was called into question in 2025 when five British mountaineers climbed Everest in...…
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  • 6 min
  • This content is machine translated Preclinical study on phytotherapeutic agent

Active ingredient combination of peppermint and caraway oil modified fecal microbiota

In an in-vitro study published in the journal Frontiers in Pharmacology in 2025, the effects of the active ingredient Menthacarin® on the composition of the human intestinal flora and the...…
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  • 4 min
  • This content is machine translated Casuistry

Rituximab used effectively against IgG4-RD colitis

IgG4-related disease (IgG4-RD) is a rare immune-mediated, fibroinflammatory disease characterized by IgG4-rich lymphoplasmacytic infiltrates with potential multiple organ involvement. Gastrointestinal manifestations are rare but may closely resemble inflammatory bowel disease,...…

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