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General Internal Medicine

1988 posts
  • This content is machine translated Chronic Pruritus in Renal, Hepatic, and Biliary Tract Diseases

Pooled Expertise for Targeted Evaluation and Treatment

According to the International Forum for the Study of Itch (IFSI), chronic pruritus can be classified into three categories. The etiological classification of pruritus on primarily non-lesional (IFSI II) skin...…
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  • 6 min
  • This content is machine translated Chronic Tinnitus

An exploratory study examined the effects of a specialized Ginkgo biloba extract

In a study population aged 21–82 years, a 24-week treatment with the specialized ginkgo extract EGb 761® resulted in significant improvements in tinnitus-related parameters overall. Subgroup analyses revealed that those...…
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  • 18 min
  • This content is machine translated From Risk Identification to Anti-Inflammatory Intervention

Inflammation as a Treatment Goal in Its Own Right

For decades, cardiovascular prevention was essentially a story about cholesterol. Yet a significant proportion of patients experience adverse events despite optimally controlled lipid levels—a reflection of a residual risk that...…
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  • 11 min
  • This content is machine translated Cardiometabolism

Retatrutid and the TRIUMPH Program: The Triple Agonist on the Horizon

Incretin-based obesity therapy has advanced rapidly in just a few years: from GLP-1 receptor agonists (semaglutide) to the dual GIP/GLP-1 agonist tirzepatide and on to a triple agonist. Retatrutide (LY3437943)...…
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  • 3 min
  • This content is machine translated Adherence and management in asthma and COPD

Better to listen to the pharmacist

Pharmaceutical care has become an important part of the management of asthma and chronic obstructive pulmonary disease (COPD). There is evidence for its role in improving adherence, optimizing pharmacotherapy and...…
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  • 4 min
  • This content is machine translated Physical activity with IBD

Sport is not murder, but it doesn’t help either

Inflammatory bowel disease (IBD) requires effective disease control to maintain quality of life and daily functioning. Physical exercise is discussed as a complementary therapy with potential immunological and psychosocial benefits....…
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  • 6 min
  • This content is machine translated Autoimmune Liver Diseases

Innovative Treatment Approaches for PBC, PSC, and AIH: What’s New?

PPAR agonists as second-line therapy have proven effective in primary biliary cholangitis (PBC) not only in clinical trials but also in real-world settings, as recent research findings show. In primary...…
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  • 4 min
  • This content is machine translated MASH

Pharmacotherapies as “Game Changers”—What Are the Upcoming Challenges?

Two drug therapy options—semaglutide (s.c.) and resmetirom (oral)—are now approved in the EU and the U.S. for the treatment of MASH. This is a major breakthrough, especially since, for a...…
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  • 13 min
  • This content is machine translated Obesity Treatment

Oral GLP-1 Therapies: ATTAIN-1 and OASIS-4—The Next Leap Forward

Injectable GLP-1 receptor agonists and the dual GIP/GLP-1 agonist tirzepatide have redefined pharmacological obesity treatment and achieved weight loss in the range of 15 to 20% in clinical trials. Nevertheless,...…
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  • 4 min
  • This content is machine translated Disorders of the Gut-Brain Interaction

Peppermint-Caraway Oil Supplement Proves Effective in Phase IV Trial

In primary care , disorders of the gut-brain axis—also known as functional gastrointestinal disorders—are very common. Herbal remedies, such as a proprietary combination of peppermint oil (Mentha × piperita L.)...…
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  • 5 min
  • This content is machine translated Gepante for Migraines

Relief from pain, symptoms, and improved functional ability—both acute and preventive

Migraine management goes beyond acute symptom control and may also include preventive strategies for patients with a significant disease burden. Although triptans remain the recommended first-line treatment for acute migraine,...…

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