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General Internal Medicine

1940 posts
  • This content is machine translated Orthobiologics for knee osteoarthritis

PRP and hyaluronic acid injections as building blocks in a multimodal concept

Conservative arthrosis therapy aims to alleviate pain and maintain mobility, whereby the measures should be individually tailored to the patient. In addition to addressing lifestyle factors, physiotherapy and physical applications...…
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  • 12 min
  • This content is machine translated The Brain and the Motivation to Eat

Why is it so hard to lose weight?

Obesity is the most common chronic disease in Western societies, with serious metabolic, cardiovascular, and psychosocial consequences. The therapeutic landscape has changed fundamentally: new-generation GLP-1 agonists achieve weight loss that,...…
CME-Test
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  • 4 min
  • This content is machine translated Hypertension: the most important facts for daily practice

Early dual antihypertensive therapy is usually indicated

95% of all hypertensive patients have primary hypertension. Over the years, the classification has evolved into a more differentiated system. The current ESC guideline, for example, differentiates between hypertension, raised...…
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  • 4 min
  • This content is machine translated Helicobacter pylori infection

Simplified dual therapy beats quadruple regimen

There are no vaccination strategies against Helicobacter pylori, a gram-negative bacterium that colonizes the gastric mucosa. Eradication relies on antimicrobial therapy to reduce transmission, promote mucosal healing and reduce the...…
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  • 5 min
  • This content is machine translated Gepante for Migraines

Relief from pain, symptoms, and improved functional ability—both acute and preventive

Migraine management goes beyond acute symptom control and may also include preventive strategies for patients with a significant disease burden. Although triptans remain the recommended first-line treatment for acute migraine,...…
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  • 3 min
  • This content is machine translated Asthma in Adults: Bronchodilation and Anti-Inflammatory Therapy

Remodeling can be counteracted through a proactive treatment strategy

If certain key, evidence-based principles are followed, remission is now an achievable goal in asthma treatment. First, it is recommended to routinely supplement spirometry with a blood test to measure...…
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  • 6 min
  • This content is machine translated Autoimmune Liver Diseases

Innovative Treatment Approaches for PBC, PSC, and AIH: What’s New?

PPAR agonists as second-line therapy have proven effective in primary biliary cholangitis (PBC) not only in clinical trials but also in real-world settings, as recent research findings show. In primary...…
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  • 5 min
  • This content is machine translated Irritable Bowel Syndrome

IBS or endometriosis?

Chronic pelvic pain ( CPP) is a common reason for referral to gynecology departments and is commonly attributed to endometriosis. However, gastrointestinal disorders, particularly irritable bowel syndrome (IBS), have several...…
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  • 6 min
  • This content is machine translated Type 2 diabetes: sarcopenia and frailty

How can the breakdown of skeletal muscles be stopped?

Insulin resistance, dyslipidemia, lack of exercise, inflammation and hypertension are among the most common risk factors for sarcopenia. Along with a loss of muscle mass and function, the risk of...…
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  • 4 min
  • This content is machine translated MASH

Pharmacotherapies as “Game Changers”—What Are the Upcoming Challenges?

Two drug therapy options—semaglutide (s.c.) and resmetirom (oral)—are now approved in the EU and the U.S. for the treatment of MASH. This is a major breakthrough, especially since, for a...…
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  • 6 min
  • This content is machine translated Treatment resistant depression

Esketamine nasal spray as monotherapy? New for treatment-resistant depression

Despite a variety of approved antidepressant treatments, major depressive disorder (MDD) remains one of the leading causes of disability worldwide and has been shown to shorten the life expectancy of...…

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