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General Internal Medicine

1931 posts
  • This content is machine translated Sarcoidosis

New options from JAKi to mTOR

Despite decades of clinical experience, the treatment of sarcoidosis remains a challenge. Although established treatment strategies such as corticosteroids, methotrexate or TNF-alpha blockers are available, the options are limited, particularly...…
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  • 4 min
  • This content is machine translated Incorrect type 2 diagnosis and SGLT2i led to DKA

Incorrect type 2 diagnosis and SGLT2i led to DKA

A patient on SGLT2 inhibitor therapy developed euglycemic diabetic ketoacidosis, which ultimately led to a diagnosis of latent autoimmune diabetes in adults (LADA). The misdiagnosis of type 2 diabetes delayed...…
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  • 15 min
  • This content is machine translated MASH and heart health

The underestimated cardiovascular threat

Metabolic-associated steatohepatitis (MASH) was long considered a purely hepatic problem. Today, data from large clinical trials and registries clearly show that cardiovascular disease is the most common cause of death...…
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  • 4 min
  • This content is machine translated Physical activity with IBD

Sport is not murder, but it doesn’t help either

Inflammatory bowel disease (IBD) requires effective disease control to maintain quality of life and daily functioning. Physical exercise is discussed as a complementary therapy with potential immunological and psychosocial benefits....…
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  • 3 min
  • This content is machine translated Adherence and management in asthma and COPD

Better to listen to the pharmacist

Pharmaceutical care has become an important part of the management of asthma and chronic obstructive pulmonary disease (COPD). There is evidence for its role in improving adherence, optimizing pharmacotherapy and...…
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  • 4 min
  • This content is machine translated Bronchiolitis obliterans

Out of shape even without popcorn

Post-infectious bronchiolitis obliterans (PIBO) develops in childhood and is characterized by irreversible airway obstruction and persistent impairment of lung function. Although it is known that exercise capacity may be impaired,...…
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  • 4 min
  • This content is machine translated Casuistry

Rituximab used effectively against IgG4-RD colitis

IgG4-related disease (IgG4-RD) is a rare immune-mediated, fibroinflammatory disease characterized by IgG4-rich lymphoplasmacytic infiltrates with potential multiple organ involvement. Gastrointestinal manifestations are rare but may closely resemble inflammatory bowel disease,...…
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  • 3 min
  • This content is machine translated IBD in childhood

Pneumococcal vaccination without negative consequences

Inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis are characterized by a relapsing-remitting course in which infectious diseases are considered important triggers for disease flare-ups. Although vaccination is...…
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  • 4 min
  • This content is machine translated Diarrhea in children

The problem of parental expectations

Acute diarrheal diseases remain a major cause of morbidity and mortality in children. Although advances in diagnostics have improved the detection of gastrointestinal pathogens, incorrect conclusions can lead to inappropriate...…
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  • 4 min
  • This content is machine translated Helicobacter pylori infection

Simplified dual therapy beats quadruple regimen

There are no vaccination strategies against Helicobacter pylori, a gram-negative bacterium that colonizes the gastric mucosa. Eradication relies on antimicrobial therapy to reduce transmission, promote mucosal healing and reduce the...…
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  • 5 min
  • This content is machine translated Irritable Bowel Syndrome

IBS or endometriosis?

Chronic pelvic pain ( CPP) is a common reason for referral to gynecology departments and is commonly attributed to endometriosis. However, gastrointestinal disorders, particularly irritable bowel syndrome (IBS), have several...…

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