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General Internal Medicine

1941 posts
  • This content is machine translated Type 2 diabetes: sarcopenia and frailty

How can the breakdown of skeletal muscles be stopped?

Insulin resistance, dyslipidemia, lack of exercise, inflammation and hypertension are among the most common risk factors for sarcopenia. Along with a loss of muscle mass and function, the risk of...…
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  • 4 min
  • This content is machine translated MASH

Pharmacotherapies as “Game Changers”—What Are the Upcoming Challenges?

Two drug therapy options—semaglutide (s.c.) and resmetirom (oral)—are now approved in the EU and the U.S. for the treatment of MASH. This is a major breakthrough, especially since, for a...…
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  • 6 min
  • This content is machine translated Treatment resistant depression

Esketamine nasal spray as monotherapy? New for treatment-resistant depression

Despite a variety of approved antidepressant treatments, major depressive disorder (MDD) remains one of the leading causes of disability worldwide and has been shown to shorten the life expectancy of...…
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  • 6 min
  • This content is machine translated Analysis of SNVCS data from the period 2005-2022

TBE vaccination for children and adolescents in Switzerland

The Swiss National Vaccination Study (SNVCS) is a nationwide cross-sectional study that evaluates the vaccination rate of children and adolescents aged 2, 8 and 16 years. In a combined cross-sectional...…
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  • 4 min
  • This content is machine translated Digital dermatology: innovative project examples

AI and eHealth tools in HS care

A key concern in the field of digital dermatology is to effectively translate scientific findings into practical digital applications. The rapid development of artificial intelligence (AI) techniques, in particular deep...…
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  • 15 min
  • This content is machine translated T helper 1 cells

Differentiation and activation of Th1 cells – a multi-omics approach

T cells are an important part of our immune system. T helper (Th) cells support and coordinate central functions of the adaptive immune response and thus contribute significantly to the...…
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  • 7 min
  • This content is machine translated Case study

8-year-old girl with Pätau syndrome aka trisomy 13

The median survival time for live-born children with complete trisomy 13 without medical intervention is 7-10 days. Over 90% of affected newborns die in the first year of life. Risk...…
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  • 6 min
  • This content is machine translated Hypertrophic cardiomyopathies (HCM)

How do myosin inhibitors perform in different HCM phenotypes?

Cardiac myosin inhibitors have been developed as a targeted therapeutic option for modulating sarcomere function. While in clinical trials in obstructive hypertrophic cardiomyopathy they brought about a greater improvement in...…
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  • 7 min
  • This content is machine translated Plastic surgery and reconstructive microsurgery for DFS

Functional limb preservation between infection control, vascular medicine and resurfacing

Diabetic foot syndrome (DFS) is one of the most serious and functionally significant complications of diabetes, with a high number of functionally relevant amputations. DFS is not to be understood...…
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  • 8 min
  • This content is machine translated Obesity treatment: new study data

Incretin mimetics for comorbidities such as type 2 diabetes, ASCVD, HF, OSAS

Lifestyle-related measures are the basic framework in the treatment of overweight and obesity. However, in order to achieve and maintain the target weight, accompanying pharmacological or surgical measures are usually...…
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  • 11 min
  • This content is machine translated Incontinence

Fecal incontinence from the perspective of gastroenterology

Fecal incontinence is a medical problem that significantly impairs the quality of life of those affected, but often remains undiagnosed and untreated due to the sufferer’s sense of shame. It...…
CME-Test

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  • 5
    Communication as the key to therapy adherence

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