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General Internal Medicine

2026 posts
  • This content is machine translated Psoriasis and Obesity: Effects of Incretin-Based Therapies

Clinical trials shed light on the potential of semaglutide, liraglutide, and tirzepatide

The bidirectional relationship between psoriasis and obesity is supported by a growing body of evidence, and it is now known that there are common inflammatory pathways. Current studies are investigating...…
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  • 7 min
  • This content is machine translated Eosinophils in the Blood in COPD

How many measurements are needed to be sure?

Approximately 20–40% of all COPD patients exhibit Type 2 inflammation, which is characterized by elevated BEC. This eosinophilic phenotype is associated with an increased risk of exacerbations and a favorable...…
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  • 6 min
  • This content is machine translated C3 glomerulopathy—can its progression be halted?

Iptacopan and Pegcetacoplan Open Up New Horizons

To diagnose C3 glomerulopathy (C3G) and distinguish it from other membranoproliferative glomerulopathies, a kidney biopsy is required in addition to measuring the concentration of the complement protein C3 in the...…
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  • 4 min
  • This content is machine translated From symptom to diagnosis

Abdominal Pain – Von Meyenburg Complexes of the Liver

Von Meyenburg complexes are believed to be a congenital malformation arising from embryonic remnants of the bile ducts. Based on current knowledge, these benign, tumor-like biliary hamartomas do not lead...…
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  • 6 min
  • This content is machine translated CKD: Cardiorenal Benefits of nsMRA and GLP-1RA

FIND-CKD and FLOW: Benefits Across Heterogeneous Patient Populations

Finerenon significantly slowed the decline in kidney function in non-diabetic adults with chronic kidney disease (CKD) and also reduced the risk of cardiovascular complications —according to recently published data from...…
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  • 8 min
  • This content is machine translated IgA Nephropathy: The Evolving Landscape of Treatment

What are the most important game-changers?

IgA nephropathy, also known as “Berger’s disease,” is the most common form of glomerulonephritis worldwide. It is an immune-mediated kidney disease diagnosed based on urine test results and a kidney...…
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  • 4 min
  • This content is machine translated Hepatitis B: New Analysis of the B-SURE Study

Bepirovir without prior nucleoside analog therapy

Innovative therapies focus either on reducing viral load or on stimulating HBV-specific immune cells—or both. The B-CLEAR study on bepirovir included two parallel cohorts: HBV patients with and without prior...…
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  • 7 min
  • This content is machine translated Lupus Nephritis – Countering the Attack on the Immune System

Innovative adjunctive therapies promote renal remission

Early diagnosis and treatment of lupus nephritis can be crucial for preserving kidney function. Among the adjunctive immunomodulatory therapies, two B-cell-targeted antibodies with different mechanisms of action—belimumab and obinutuzumab—are now...…
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  • 9 min
  • This content is machine translated Congenital Vascular Malformations

Personalized Treatment Before a Planned Pregnancy

Vascular malformations have a prevalence of 1% and an incidence of 3–5 per 10,000. Anomalies can affect any organ system in children and adults. Mosaic mutations occurring during embryonic development...…
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  • 8 min
  • This content is machine translated Hyperhidrosis: Keep a Cool Head

An Overview of Important Treatment Options

Excessive sweating can significantly impair quality of life. Gravimetry and the iodine-starch test are important diagnostic methods. Various options are available for the conservative treatment of primary hyperhidrosis. Topical preparations...…
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  • 4 min
  • This content is machine translated 2026 Vaccination Schedule: Important Changes

Updated Recommendations on Pneumococcal Disease and RSV

Competent medical counseling can help promote acceptance of vaccinations. To this end, it is crucial to always have the most up-to-date information. The current immunization schedule includes several relevant changes...…

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