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General Internal Medicine

1988 posts
  • This content is machine translated Why the Finerenon Boom Is Giving Hyperkalemia Treatment New Relevance

Potassium binders as enablers of RAASi optimization

Renin-angiotensin-aldosterone system (RAAS) inhibitors—including mineralocorticoid receptor antagonists (MRAs)—are among the most effective tools in cardiorenal medicine. However, their benefits are often undermined in everyday clinical practice because fear of hyperkalemia...…
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  • 3 min
  • This content is machine translated Asthma in Adults: Bronchodilation and Anti-Inflammatory Therapy

Remodeling can be counteracted through a proactive treatment strategy

If certain key, evidence-based principles are followed, remission is now an achievable goal in asthma treatment. First, it is recommended to routinely supplement spirometry with a blood test to measure...…
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  • 3 min
  • This content is machine translated From symptom to diagnosis

Gynecomastia and Adipomastia

The term ” gynecomastia ” refers to the enlargement of the mammary gland in men, which may be unilateral or bilateral. True gynecomastia, caused by an increase in glandular tissue,...…
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  • 7 min
  • This content is machine translated Plastic surgery and reconstructive microsurgery for DFS

Functional limb preservation between infection control, vascular medicine and resurfacing

Diabetic foot syndrome (DFS) is one of the most serious and functionally significant complications of diabetes, with a high number of functionally relevant amputations. DFS is not to be understood...…
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  • 12 min
  • This content is machine translated SURPASS-CVOT

Tirzepatide versus Dulaglutide in T2D with ASCVD

GLP-1 receptor agonists have established themselves in recent years as a class of drugs with cardiovascular protective effects in type 2 diabetes. For dulaglutide, the 2019 REWIND study showed that...…
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  • 6 min
  • This content is machine translated Secondary prevention after ACS: individually optimized lipid management

Trend towards early combination therapy and new strategies for lowering Lp(a)

Secondary prevention after an acute coronary syndrome (ACS) is crucial for improving quality of life and reducing morbidity and mortality rates. Elevated blood lipid levels such as LDL cholesterol and...…
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  • 5 min
  • This content is machine translated CKD in People with Type 2 Diabetes: Evidence-Based, Optimized Treatment

SGLT-2 inhibitors and GLP-1 receptor agonists: significant improvement in renal outcomes

Approximately 30–40% of patients with type 2 diabetes develop chronic kidney disease (CKD) over time. In “landmark” studies such as CREDENCE, DAPA-CKD, EMPA-KIDNEY, and several others, SGLT-2 (sodium-glucose-linked transporter 2)...…
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  • 13 min
  • This content is machine translated Planning a Family, Pregnancy, and Breastfeeding

Update on Anti-Rheumatic Medications

The 2024 EULAR recommendations on the use of antirheumatic medications during reproduction, pregnancy, and breastfeeding replace the previous recommendations from 2016. During this period, studies on the safety of biologics...…
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  • 5 min
  • This content is machine translated Mental Health with GLP-1 RAs

Benefits of Semaglutide and Liraglutide

GLP-1 receptor agonists are established treatments for type 2 diabetes and obesity. Depression and anxiety disorders are common among people with diabetes and obesity, and both conditions are associated with...…
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  • 4 min
  • This content is machine translated Bronchiolitis obliterans

Out of shape even without popcorn

Post-infectious bronchiolitis obliterans (PIBO) develops in childhood and is characterized by irreversible airway obstruction and persistent impairment of lung function. Although it is known that exercise capacity may be impaired,...…
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  • 12 min
  • This content is machine translated The Brain and the Motivation to Eat

Why is it so hard to lose weight?

Obesity is the most common chronic disease in Western societies, with serious metabolic, cardiovascular, and psychosocial consequences. The therapeutic landscape has changed fundamentally: new-generation GLP-1 agonists achieve weight loss that,...…
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