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General Internal Medicine

2026 posts
  • This content is machine translated Planning a Family, Pregnancy, and Breastfeeding

Update on Anti-Rheumatic Medications

The 2024 EULAR recommendations on the use of antirheumatic medications during reproduction, pregnancy, and breastfeeding replace the previous recommendations from 2016. During this period, studies on the safety of biologics...…
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  • 7 min
  • This content is machine translated Juvenile Idiopathic Arthritis

Early Detection and Targeted Treatment in an Interdisciplinary Setting

Juvenile idiopathic arthritis is the most common autoimmune disease in childhood—the incidence among children under 16 is approximately 1 in 1,000. Early diagnosis and appropriate treatment remain a challenge. As...…
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  • 6 min
  • This content is machine translated Wrinkle Treatment with Botulinum Toxin: Current Trends

The “Hotspots” Theory and the Moose Injection Technique

A recent review article summarized findings on motor microinnervation and the topography of neuromuscular end plates in the muscles of the upper half of the face to facilitate the best...…
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  • 5 min
  • This content is machine translated Rare Pathogens in CAP

When pneumonia is not “typical”

Rare pathogens causing community-acquired pneumonia (CAP) represent clinically relevant differential diagnoses—particularly in cases of atypical clinical courses, lack of response to treatment, or unusual imaging findings. Filamentous bacteria such as...…
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  • 6 min
  • This content is machine translated Disorders of the Gut-Brain Interaction

Rome V Criteria: What Has Changed, and What Has Remained the Same?

Disorders of the gut-brain interaction (DGBI) are characterized by gastrointestinal symptoms resulting from a combination of various factors—including motility disorders, visceral hypersensitivity, and dysbiosis. For many years, research into and...…
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  • 5 min
  • This content is machine translated New COPD Treatments

Targeting the inflammation—but for whom and when?

Up to 50% of people with COPD continue to experience exacerbations despite receiving maximum inhaled therapy. The key factor here is persistent chronic inflammation, which cannot be fully controlled even...…
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  • 5 min
  • This content is machine translated Tourette Syndrome

What can be done to treat this tic disorder?

Gilles de la Tourette syndrome (or “Tourette syndrome” for short) is a neurodevelopmental disorder characterized by motor and vocal tics and often accompanied by attention deficits, hyperactivity, and obsessive-compulsive disorder....…
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  • 4 min
  • This content is machine translated Chronic Hepatitis B: Is a Cure in Sight?

Phase III Trial of Temporary Treatment with Bepirovirsen Was Successful

Hepatitis B is the most common form of viral hepatitis worldwide—dreaded complications include liver cirrhosis and hepatocellular carcinoma (HCC). Treatment with Bepirovirsen, an antisense oligonucleotide that targets mRNAs of the...…
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  • 14 min
  • This content is machine translated Fibromyalgia Syndrome

Development, Diagnosis, Epidemiology, and Treatment of a Disease Entity

According to the 2010 and 2011 ACR diagnostic criteria, as revised in 2016, fibromyalgia syndrome is a multisymptomatic disorder whose primary symptom is chronic tendon-muscle pain that shifts and spreads...…
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  • 5 min
  • This content is machine translated Clinically Suspected Arthralgias

“Watchful waiting” or intervention?

The pathogenesis of rheumatoid arthritis (RA) begins years before clinical manifestation, but not all patients with joint pain develop RA. Since the primary care physician or internist’s office is usually...…
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  • 6 min
  • This content is machine translated Upper GI Tract Bleeding: Hematemesis, Hematochezia, or Melena?

From Risk Stratification to Post-Endoscopic Management

Managing patients with acute upper gastrointestinal bleeding can be a balancing act. Clinical scores are helpful for time-sensitive risk assessment in the emergency department: Is the patient stable? Is urgent...…

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