This content is machine translated DPP4 inhibitor in adolescents with type 1 diabetes Sitagliptin add on shows renoprotective effect Children with type 1 diabetes have an increased risk of developing diabetic kidney disease (DKD). Inhibition of dipeptidyl peptidase-4 (DPP4) has positive effects on various metabolic indicators in diabetes. Egyptian…
View Post 5 min This content is machine translated Rare diseases Fanconi-Bickel syndrome Fanconi-Bickel syndrome (FBS) occurs due to variants in the SLC2A2 gene. The diagnosis of a rare genetic disease can take up to 5-6 years, even longer in low and middle…
View Post 5 min This content is machine translated Journal Club Nephrolithiasis and gout: SGLT2i could be an effective supplement Nephrolithiasis and gout are diseases with an increasing global burden and often co-occur with type 2 diabetes mellitus. SGLT2 inhibitors, which were first approved for the treatment of hyperglycemia in…
View Post 4 min This content is machine translated The endocrine basis of the cardiorenal axis New perspectives on the role of Corin In recent decades, the central role of natriuretic peptides (NPs) in the interaction between the heart and kidneys has been uncovered. These peptides, especially the atrial natriuretic peptide (ANP) and…
View Post 6 min This content is machine translated Birt-Hogg-Dubé syndrome Fibrofolliculomas as indicator lesions The vast majority of patients affected by this rare hereditary tumor syndrome develop numerous fibrofolliculomas in middle age, particularly on the face and upper body. Genetic testing is required to…
View Post 14 min This content is machine translated Kidney cancer Palliative systemic therapy for metastatic renal cell carcinoma Renal cell carcinoma (RCC) is the most common malignant disease of the kidney. There are currently no established predictive biomarkers to guide palliative therapy with checkpoint inhibitors (CPI), tyrosine kinase… CME-Test
View Post 4 min This content is machine translated Casuistry SLE with kidney damage does not always have to be lupus nephritis The distinction between IgA nephropathy and lupus nephritis in patients with systemic lupus erythematosus (SLE) has important prognostic and therapeutic implications. Physicians from China describe a case of systemic lupus…
View Post 5 min This content is machine translated Type 2 diabetes: reduction of microvascular and macrovascular risks The extensive toolbox has a lot to offer The fact that most type 2 diabetics today aim for an HbA1c value of <7% is partly due to the results of the UKPDS. This landmark study showed that the…
View Post 9 min This content is machine translated Blood pressure control in renal and cardiac patients Hypertensive diseases in pregnancy During pregnancy, progesterone causes a drop in blood pressure. Physiologically, this can be attributed on the one hand to the increase in venous vascular capacity (dilatation of the vascular system… CME-Test
View Post 14 min This content is machine translated Kidney cancer Palliative systemic therapy for metastatic renal cell carcinoma Renal cell carcinoma (RCC) is the most common malignant disease of the kidney. There are currently no established predictive biomarkers to guide palliative therapy with checkpoint inhibitors (CPI), tyrosine kinase… CME-Test
View Post 4 min This content is machine translated Hypomagnesemia Renal or extrarenal causes? In one of this year’s issues of the American Journal of Kidney Diseases, the official publication of the National Kidney Foundation, an article on magnesium metabolism disorders has been published.…