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Pharmacology and toxicology

255 posts
  • This content is machine translated Phytotherapy against allergic rhinitis

Efficacy of butterbur extract Ze 339 repeatedly proven

In medicine, too, coincidence sometimes helps: employees of a pharmaceutical company took a butterbur preparation from their company for headaches and as a result suddenly noticed much fewer hay fever…
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  • 4 min
  • This content is machine translated Metastatic renal cell carcinoma.

What are the reasons for resistance to current drugs?

Practical strategies for treatment management of metastatic renal cell carcinoma (mRCC) were presented at the ESMO Congress in Amsterdam. Updates on current clinical trials and the utility of new treatment…
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  • 5 min
  • This content is machine translated New drugs

Optimal use of kinase inhibitors

How can kinase inhibitors be put to good use? What are the advantages or disadvantages of a combination? How can genomic sequencing contribute to an individualized therapeutic approach with such…
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  • 3 min
  • This content is machine translated Decrease of brain volume in multiple sclerosis

Potential future parameter for therapy monitoring

More and more is becoming known about the importance of decreasing brain volume in patients with multiple sclerosis. And this is not least thanks to steady progress in imaging techniques…
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  • 6 min
  • This content is machine translated Non-Hodgkin's lymphoma and myelodysplastic syndrome

What are the benefits of lenalidomide and pomalidomide?

At the ASH Congress in New Orleans, the focus was on the efficacy and safety of lenalidomide plus low-dose dexamethasone in the treatment of patients with newly diagnosed multiple myeloma.…
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  • 6 min
  • This content is machine translated COPD exacerbation

Five days of prednisone 40 mg is enough

Background: In Switzerland, about 5-7% of the population and certainly 28% of smokers suffer from COPD (“chronic obstructive pulmonary disease”). Acute exacerbation of COPD is a risk factor for further…
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  • 4 min
  • This content is machine translated Treatment of metastatic colorectal carcinoma.

Patients with RAS wild type benefit in overall survival

New data on first-line treatment of metastatic colorectal cancer were presented at the ASCO GI in San Francisco. The post-hoc analyses consistently confirm that RAS mutation status is an important…
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  • 6 min
  • This content is machine translated Tyrosine kinase inhibitors and the skin

From common to rare side effects

Epidermal-growth-factor receptors are found in the skin and sebaceous glands, tyrosine kinase (TK) in keratinizing skin, mucous membranes and hair, and are thus also targets of EGFR- and TK-inhibiting oncologics…
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  • 3 min
  • This content is machine translated EPs 7630 against bronchitis

A plant extract with high evidence

Pelargonium sidoides, a plant native to southern Africa, has been studied by various research teams since the 1990s. Folk application against bronchitis gave the medical evidence, also a meta-analysis confirmed…
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  • 8 min
  • This content is machine translated Immunotherapy and immunomodulation

Disease-modifying therapies for multiple sclerosis.

Multiple sclerosis is the most common neurological disease in young adults. Already at a young age it can lead to permanent disability, but the disease activity at the beginning of…
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  • 11 min
  • This content is machine translated Stop smoking

Information for daily practice

It is undisputed that smoking is harmful and among the most important causes of premature morbidity and mortality. Because of the serious health consequences, smoking cessation counseling is important and…

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