This content is machine translated News from the lung cancer pipeline First targeted substance in KRAS mutation and bispecific immunotherapy While targeted therapies in non-small cell lung cancer (NSCLC) have been on the rise for years, such an option for KRAS-mutatedtumors has been lacking. The small molecule inhibitor Sotorasib, which…
View Post 3 min This content is machine translated Severe eosinophilic asthma Small airways as a predictor of biologics Biologic anti-T2 therapies can effectively reduce acute exacerbations and the need for daily doses of oral steroids in severe eosinophilic asthma. However, expiratory flow (FEV1) benefits little and shows only…
View Post 4 min This content is machine translated Pulmonary embolism Anticoagulate hemodynamically unstable patients even on suspicion Patients with pulmonary embolism require anticoagulation for a period of at least three months. Before starting therapy, several considerations must be addressed: Which anticoagulant is the most appropriate for this…
View Post 3 min This content is machine translated Reflux Also of interest to the pulmonologist In Western countries, GERD (gastroesophageal reflux disease) affects approximately 20% of the population. Normally, the route leads to the gastroenterologist, but because the food pathway and the airway cross at…
View Post 4 min This content is machine translated Alpha-1 antitrypsin deficiency It does not always have to be obstruction A 52-year-old female patient has been suffering from recurrent infections for years and requires recurrent antibiotics. No other diseases are present. The reason was alpha-1 antitrypsin deficiency. Bronchiectasis can lead…
View Post 2 min This content is machine translated Non-small cell lung cancer with EGRF mutation. New approval for osimertinib for adjuvant therapy Following convincing results from the Phase III ADAURA study, the indication for osimertinib was expanded in Switzerland. Thus, the drug may now also be used for adjuvant therapy in early-stage…
View Post 5 min This content is machine translated Parkinson's disease What to do in case of respiratory disorders? Pneumologic and neurologic dysfunction occur equally in PD and are typical of the disease. It is therefore important to be mutually considerate: Pneumologists must not disregard the fact that respiratory…
View Post 7 min This content is machine translated Non-infectious complications after HSCT Cure for multiple sclerosis at any price? Hematopoietic stem cell transplantation (HSCT) is used as ultima ratio in multiple sclerosis. The reboot of the immune system is aimed at healing, but carries strong side effects. Both infectious…
View Post 5 min This content is machine translated Moderate asthma What drives the physician’s therapy decision When treating asthma patients, many thoughts run through the physician’s mind – after all, on the one hand he usually has several therapy options, but on the other hand he…
View Post 2 min This content is machine translated GINA Guideline 2020 New weapon at level 5 The Global Initiative for Asthma (GINA) has also updated its recommendations for asthma management in 2020. The most important announcement in it for the occasion: during the COVID-19 pandemic, patients…
View Post 11 min This content is machine translated Thoracic surgery operations Prevention and treatment of respiratory and cardiac disorders. Any surgery can cause problems with the circulation, heart or lungs postoperatively. The prevention of such complications and their treatment is of great importance, because otherwise the perioperative risk increases… CME-Test
