This content is machine translated Arterial elasticity, vascular ageing, endothelial function Longevity and cardiovascular health 2025 Vascular ageing is not a purely “biological” concept, but can be measured clinically – via arterial stiffness (e.g. PWV), endothelial function (e.g. FMD) and the resulting risk profiles. In parallel...…
View Post 5 min This content is machine translated AI-supported risk stratification for chest pain in the emergency room Performance of a fully automated ECG model Despite guidelines, the standardized assessment of chest pain in the emergency department remains inconsistent, expensive and prone to misinterpretation. A retrospective two-center study approach published in Open Heart now presents...…
View Post 6 min This content is machine translated Hormone balance and longevity Ageing is not a substitution diagnosis In the longevity debate, “hormone balance” is often used as a synonym for “biologically younger”. Clinically, the term is only meaningful if it is linked to clearly defined axial disorders,...…
View Post 6 min This content is machine translated Cardiovascular risk Bad news for young men with T2D Cardiovascular disease ( CVD) remains the leading cause of death and disease worldwide, and people with type 1 or type 2 diabetes are at higher risk than the general population....…
View Post 20 min This content is machine translated AI in neurology Control instead of a flood of data: AI makes big data and wearables usable Artificial intelligence has become a key technology in medicine, including in complex neurology. Modern methods such as machine learning and deep learning in combination with data and wearables (wearable sensor...… CME-Test
View Post 9 min This content is machine translated Neuroprotection, resilience and cognitive health in old age Longevity & Brain Cognitive health in old age is not an inevitable fate, but can be influenced to a relevant extent by modifiable factors. The Lancet Commission 2024 concludes that a significant proportion...…
View Post 6 min This content is machine translated Obesity as a chronic disease: an interdisciplinary perspective Neurobiological mechanisms of obesity A high-fat and high-sugar diet affects both the homeostatic hunger and satiety signals in the hypothalamus and the hedonic reward system, leading to persistent hunger and a strong craving for...…
View Post 4 min This content is machine translated Therapy of non-tumor-related pain Do not prescribe opioids lightly for musculoskeletal pain A UK research team used electronic primary care patient records from 2006-2021 based on the Clinical Research Practice Datalink (CPRD) to identify opioid prescriptions. The analyses revealed that almost three...…
View Post 6 min This content is machine translated RSV infection in adult patients at risk Vaccination as a simple and sensible prophylaxis RSV infections in adults are roughly comparable to seasonal flu. Although their course is often mild, there are a number of risk factors for a severe course involving the lower...…
View Post 6 min This content is machine translated Oncology Study updates from the ESMO Congress The variety of topics presented at the congress of the European Society for Medical Oncology (ESMO) last October underlined the breadth of the field and the close interlinking of disciplines....…
View Post 10 min This content is machine translated A hub of biological aging Mitochondrial dysfunction and energy metabolism Mitochondrial dysfunction is not defined as an isolated “ATP problem” in the Hallmarks of Ageing framework, but as a systemic shift in bioenergetics, redox signaling, quality control and immune metabolism....…
