This content is machine translated Chronic inflammation as a driver of ageing Immunosenescence and inflammaging Immunosenescence and inflammaging are now regarded as central biological mechanisms of ageing. The age-related altered immune system is both weakened and chronically activated – with consequences for susceptibility to infection,...…
View Post 12 min This content is machine translated Endometrial carcinoma, malignant melanoma and NSCLC in focus Personalized mRNA and neoantigen vaccines in oncology mRNA technology has experienced its global breakthrough as a result of the COVID-19 pandemic and has long been clinically established. In oncology, however, the actual translation is only now beginning....…
View Post 6 min This content is machine translated RSV infection in adult patients at risk Vaccination as a simple and sensible prophylaxis RSV infections in adults are roughly comparable to seasonal flu. Although their course is often mild, there are a number of risk factors for a severe course involving the lower...…
View Post 7 min This content is machine translated A case-based, practical overview from Canada Vaccinations for heart patients Patients with cardiovascular disease (CVD) are more likely to suffer severe courses of vaccine-preventable infections – and more cardiac complications such as ACS, heart failure decompensation, arrhythmias or strokes. This...…
View Post 7 min This content is machine translated Focus on new therapeutic targets and senolytics Cellular senescence Cellular senescence is considered a key biological program that can exert both protective and potentially pathogenic effects in tissues across the lifespan. If senescent cells persist, they are associated with...…
View Post 7 min This content is machine translated Arterial elasticity, vascular ageing, endothelial function Longevity and cardiovascular health 2025 Vascular ageing is not a purely “biological” concept, but can be measured clinically – via arterial stiffness (e.g. PWV), endothelial function (e.g. FMD) and the resulting risk profiles. In parallel...…
View Post 5 min This content is machine translated AI-supported risk stratification for chest pain in the emergency room Performance of a fully automated ECG model Despite guidelines, the standardized assessment of chest pain in the emergency department remains inconsistent, expensive and prone to misinterpretation. A retrospective two-center study approach published in Open Heart now presents...…
View Post 6 min This content is machine translated Hormone balance and longevity Ageing is not a substitution diagnosis In the longevity debate, “hormone balance” is often used as a synonym for “biologically younger”. Clinically, the term is only meaningful if it is linked to clearly defined axial disorders,...…
View Post 6 min This content is machine translated Cardiovascular risk Bad news for young men with T2D Cardiovascular disease ( CVD) remains the leading cause of death and disease worldwide, and people with type 1 or type 2 diabetes are at higher risk than the general population....…
View Post 20 min This content is machine translated AI in neurology Control instead of a flood of data: AI makes big data and wearables usable Artificial intelligence has become a key technology in medicine, including in complex neurology. Modern methods such as machine learning and deep learning in combination with data and wearables (wearable sensor...… CME-Test
View Post 9 min This content is machine translated Neuroprotection, resilience and cognitive health in old age Longevity & Brain Cognitive health in old age is not an inevitable fate, but can be influenced to a relevant extent by modifiable factors. The Lancet Commission 2024 concludes that a significant proportion...…
