This content is machine translated Myelofibrosis Treatment in transition With the introduction of the Janus kinase (JAK) inhibitor ruxolitinib, therapy for myelofibrosis has changed dramatically in recent years. Nevertheless, further innovation is needed, especially in the second line. Promising…
View Post 6 min This content is machine translated Diabetic polyneuropathy Measure nerve conduction velocity for diagnosis Diabetic polyneuropathy (dPNP) is the most common neuropathy in Western countries. But who gets them and how do you recognize them? This question is particularly important because 40% of those…
View Post 5 min This content is machine translated Gastroesophageal reflux disease (GERD) Alginate as an as-needed add-on therapy increases patient satisfaction The standard therapy for treating all manifestations of reflux disease is proton pump inhibitors (PPI). Despite a high success rate, there are occasional patients with an insufficient response to therapy.…
View Post 2 min This content is machine translated Lipid Management Guideline-compliant care up to date A fundamental factor in the field of cardiology is LDL cholesterol. Because without cholesterol, there is no atherosclerosis. Therefore, effective lipid management is paramount for the prevention of cardiovascular events.…
View Post 5 min This content is machine translated Functional gastrointestinal disorders Combination of peppermint and caraway oil significantly reduces visceral hyperalgesia Visceral hyperalgesia plays an important role in the pathomechanism of functional gastrointestinal complaints. Symptom-oriented analgesic treatment can modulate the pain threshold. The analgesic effects of menthacarin have been demonstrated in…
View Post 4 min This content is machine translated Acute generalized exanthematous pustulosis (AGEP). Not just a T cell-mediated disease? Immunopathological studies have shown that not only T cells play a role in drug reactions, especially in AGEP, but also IL36 cytokines and other mediators are involved. These findings are…
View Post 3 min This content is machine translated SGLT2 inhibitors Cardioprotective effect proven and found to be good – a statement One of the serious long-term consequences of diabetes mellitus is cardiovascular disease. Heart failure, in particular, is common in patients who have had diabetes for a long time. Recent study…
View Post 3 min This content is machine translated Digital Health Great interest in telemedical services – not only corona-related During the COVID 19 pandemic, the use of digital services has continued to gain currency. The results of the Digital Health Survey show that demand was already high. The interim…
View Post 6 min This content is machine translated Connective tissue diseases Early detection and treatment of localized scleroderma in children In progressive forms and extensive linear expression of the lesions, deformities and movement restrictions may occur if left untreated. Early diagnosis enables adequate treatment measures and sustainable long-term management. This…
View Post 4 min This content is machine translated Digital Health Technology Artificial Intelligence and “Big Data” – also a trend in dermatology Especially in the field of medical image recognition, artificial intelligence (AI) applications are widely developed, which is a very interesting application area for dermatology. For an adequate implementation of digital…
View Post 3 min This content is machine translated Angina pectoris Antianginal therapy shows no long-term benefit for prophylaxis Angina may persist or recur despite successful revascularization with percutaneous coronary intervention. In these cases, antianginal treatment is supplemented. To demonstrate the effectiveness of this approach, a clinical trial was…