This content is machine translated Therapy of non-tumor-related pain Do not prescribe opioids lightly for musculoskeletal pain A UK research team used electronic primary care patient records from 2006-2021 based on the Clinical Research Practice Datalink (CPRD) to identify opioid prescriptions. The analyses revealed that almost three...…
View Post 3 min This content is machine translated Migraine Fremanezumab for comorbid migraine and depression Migraine and depression often reinforce each other and make treatment more difficult. The UNITE study shows that the CGRP antibody fremanezumab significantly reduces both migraine days and depressive symptoms –...…
View Post 6 min This content is machine translated Case study Moyamoya disease in a 23-year-old female patient Moyamoya disease is characterized by progressive narrowing of the internal carotid arteries and their branches. This can lead to ischemic and/or hemorrhagic disorders of the cerebral circulation. According to the...…
View Post 6 min This content is machine translated Dapagliflozin for T2D and heart failure Epicardial fat reduced in patients with type 2 diabetes and HF The co-occurrence of heart failure (HF) and diabetes leads to a higher risk of complications, higher mortality and worse outcomes than either disease alone. Studies have shown the importance of...…
View Post 10 min This content is machine translated A hub of biological aging Mitochondrial dysfunction and energy metabolism Mitochondrial dysfunction is not defined as an isolated “ATP problem” in the Hallmarks of Ageing framework, but as a systemic shift in bioenergetics, redox signaling, quality control and immune metabolism....…
View Post 3 min This content is machine translated Health Literacy Promoting health literacy: from the abstract to the concrete level The Federal Council’s health policy strategy “Health 2030” sets out a framework for action in health policy aimed at securing healthcare provision in the coming years. The second of the...…
View Post 8 min This content is machine translated Pharmacological therapy Anxiety symptoms in eating disorders Eating disorders are mental illnesses that are strongly influenced by biological, psychological and social stress factors. Anxiety symptoms are among the most common and most impairing accompanying symptoms. The systematic...…
View Post 4 min This content is machine translated Case study Wiedemann-Steiner syndrome in a 2-year-old girl The patient, who had a phenotype characterized by hypertelorism, thick eyebrows and other features, was found to have a c.517C>T nonsense mutation in the KMT2A gene. This rare heterozygous mutation...…
View Post 4 min This content is machine translated Chronic back pain Care in the virtual hospital – the Back@home project As part of the Back@Home study, the effectiveness of a virtual hospital model is being evaluated in patients with musculoskeletal back pain who present to the emergency room. One of...…
View Post 4 min This content is machine translated Psoriatic arthritis Long-term remission also possible without DMARDs Remission without disease-modifying antirheumatic drugs has become an ambitious goal in inflammatory rheumatic diseases. While it has been extensively studied in rheumatoid arthritis, its feasibility in psoriatic arthritis (PsA) has...…
View Post 5 min This content is machine translated Clinical relevance, benefits and limitations Atrial Fibrillation Screening Screening for atrial fibrillation is considered a potentially effective strategy for preventing strokes at an early stage. But how great is the actual benefit in clinical care? A recent meta-analysis...…
