This content is machine translated Heart failure Pharmacotherapy in HFrEF and HFmrEF – Combination of four as gold standard. Important therapeutic goals in chronic heart failure are to improve quality of life and to reduce the risk of hospitalization and mortality. According to current evidence, guideline-based therapy with the…
View Post 3 min This content is machine translated Cutaneous T-cell lymphoma (CTCL) First targeted antibody approved for CTCL patients with MF or SS The approval of the anti-CCR4 antibody mogamulizumab provides patients with cutaneous T-cell lymphoma (CTCL) of the mycosis fungoides (MF) and Sézary syndrome (SS) subtypes with an effective non-chemotherapeutic intervention for…
View Post 2 min This content is machine translated Onychomycoses: cohort study. Comparison of molecular diagnostic and conventional methods An international research team involving the University Hospitals of Lausanne and Zurich has compared different diagnostic methods in a large-scale retrospective study. In agreement with previous empirical findings, the conclusion…
View Post 6 min This content is machine translated Atopic dermatitis Skin microbiome normalizes under tralokinumab therapy Atopic dermatitis is associated with dysbiosis of the cutaneous microbiome. Characteristic is reduced bacterial diversity, with Staphylococcus aureus often being the dominant bacterial genus. In a recent study, it was…
View Post 5 min This content is machine translated Specialist guideline asthma New recommendations for the everyday life of specialists The national S3 care guideline on bronchial asthma in Germany was updated in 2020. This guideline also has acceptance in Switzerland and has a very high level of evidence, but…
View Post 7 min This content is machine translated Myositides The most important guideline recommendations at a glance The German Society of Neurology (DGN) has issued an updated S2k guideline on myositis syndromes in 2022. In recent years, new therapeutic studies have helped improve treatment strategies. There have…
View Post 6 min This content is machine translated Atopic eczema EuroGuiDerm guideline – overview of current recommendations for system therapy Recently, there have been significant advances in the treatment of atopic dermatitis, including several new systemic therapeutic options overcoming regulatory hurdles. This has also been incorporated into the EuroGuiDerm guideline…
View Post 5 min This content is machine translated Corona Pandemic Current findings on Long-Covid – initial treatment options and therapeutic approaches. In the Zurich Coronavirus Cohort Study, one in four participants reported persistent symptoms six months after SARS-CoV-2 infection. What are the underlying pathophysiological mechanisms of long-covid? Which treatment strategies are…
View Post 4 min This content is machine translated Study Report Benefit of thrombectomy after ischemic cerebral infarction. As recent empirical data show, patients with occlusions of a large artery in the anterior cerebral circulation, if they have large core volumes, benefit from additional endovascular stroke therapy in…
View Post 3 min This content is machine translated Plaque psoriasis New “Real World” Study on Tildrakizumab In a retrospective study of 30 patients with moderate to severe plaque psoriasis, the use of the IL-23 inhibitor tildrakizumab was shown to be effective and safe in clinical practice.…
View Post 4 min This content is machine translated Hemostaseology New concepts for a lifelong challenge – tumor-associated VTE. There has been a groundbreaking increase in knowledge in hemostaseology in recent years, both preclinically in basic research and clinically with the development of innovative treatment strategies. Using the patient…
