This content is machine translated Psoriatic arthritis (PsoA) Pooled analysis on the efficacy of secukinumab from four phase III studies Improvement in clinical endpoints was seen with secukinumab treatment regardless of latency since initial psoriatic arthritis diagnosis, with patients diagnosed less than one year ago showing a slightly better response…
View Post 5 min This content is machine translated Immunotherapy Untapped potential in early disease stages Over the last decade, immunotherapy using checkpoint inhibitors has become established in the treatment of many oncological conditions. Especially in advanced tumor disease, ipilimumab, nivolumab and co. play a significant…
View Post 5 min This content is machine translated The metabolic patient Type 2 diabetes: reducing cardiovascular risk through lipid lowering Diabetes is associated with increased cardiovascular risk. Multifactorial therapy of the four major risk factors of blood glucose, weight, hypertension, and dyslipidemia in individuals with type 2 diabetes is challenging.…
View Post 4 min This content is machine translated SARS-CoV-2 Pelargonium sidoides shows antiviral and immunomodulatory effects in vitro. Currently available treatment options against Covid-19 are very limited and research for effective drugs is feverish. An international team of scientists recently published results of a preclinical in vitro study indicating…
View Post 6 min This content is machine translated Hypopigmentation New guideline on vitiligo According to experts, vitiligo is a chronic skin disease and not just a cosmetic problem. The S1 guideline, published under the auspices of the German Dermatological Society, summarizes current evidence-based…
View Post 3 min This content is machine translated Type 2 diabetics with overweight Dulaglutide in higher dosage additionally promotes weight reduction GLP-1 receptor agonists not only improve glycemic control but also support weight loss and have also demonstrated additional cardio- and neprotective benefits. Dulaglutide (s.c.) has been successfully used for the…
View Post 4 min This content is machine translated Atopic dermatitis Long-term efficacy of baricitinib proven In adult patients with moderate to severe atopic dermatitis, long-term therapy with the JAK inhibitor baricitinib maintained improvements achieved after 16 weeks for 68 weeks, new data show. A pooled…
View Post 4 min This content is machine translated Systemic lupus erythematosus Innovative therapeutic approaches on the rise – pioneering new treatment strategies Systemic lupus erythematosus (SLE) carries a high risk of life-threatening organ damage, but there is new hope for sufferers. In recent years, the development of innovative treatment options has been…
View Post 3 min This content is machine translated Statistics in 5 minutes Statistical tests: Of sharpness and power The goal of every study and every statistical test is to reliably demonstrate effects that are actually present and sometimes not clearly apparent at first glance. However, often only a…
View Post 3 min This content is machine translated ART: "single tablet" regimen with triple combination. Compelling “real world” data in HIV patients over 65 years of age. There are increasing numbers of older people living with HIV, but the 65+ age group is generally underrepresented in clinical trials. An ongoing study in a “real world” setting is…
View Post 4 min This content is machine translated Amyotrophic lateral sclerosis (ALS) Risk factor heavy physical work Researchers at Ulm University Medical Center have identified heavy physical labor as a risk factor for the incurable nerve disease amyotrophic lateral sclerosis (ALS). In their technical publication, which is…
