This content is machine translated Diffuse large B-cell lymphoma (DLBCL) Innovative Salvage Therapy for Advanced DLBCL Diffuse large B-cell lymphoma is the most common type of non-Hodgkin lymphoma. If left untreated, accumulations of lymphoma cells impede the function of affected organs and lead to the death…
View Post 4 min This content is machine translated Moderate to severe atopic dermatitis IL-13 blockade – an innovative treatment approach with great potential The spectrum of systemic treatment options for atopic dermatitis is currently in flux. In recent years, the interleukin (IL)-13 pathway has been shown to play an essential role in the…
View Post 4 min This content is machine translated Alzheimer Amyloid and tau are a dangerous pair In the course of Alzheimer’s disease, the proteins “amyloid” and “tau” accumulate in the brain. A DZNE study with more than 200 participants now provides insights into the interplay of…
View Post 4 min This content is machine translated SARS-CoV2 Changes in brain structure over the long-term in non-hospitalized subjects. Using data from the longitudinal “UK Biobank” initiated in the pre-pandemic era, cerebral MRI findings before and after COVID-19 were collected for the first time in the same individuals and…
View Post 3 min This content is machine translated Nephrology What is good for the kidneys also supports the heart – and vice versa The kidneys and the heart form a finely tuned construct. If the balance gets out of sync, this has an effect on both organs. The SGLT2 inhibitors originally developed for…
View Post 5 min This content is machine translated Late effects of Covid-19 Long Covid: dermatological aspects In some patients, chronicizing symptoms develop after the acute phase of Covid-19 infection. In the S1 guidelines on Long-Covid published by various professional societies, this is highlighted from an interdisciplinary…
View Post 3 min This content is machine translated Non-small cell lung cancer Who benefits from targeted therapy? A large multicenter study led by the DKFZ-Hector Cancer Institute at the University Medical Center Mannheim confirms substantial differences in treatment response and provides important insights for treatment planning.
View Post 9 min This content is machine translated Locally advanced/metastatic breast carcinoma 44th San Antonio Breast Cancer Symposium: Best Of From December 7-10, 2021, the 44th San Antonio Breast Cancer Symposium took place in a physical-virtual hybrid event. In a series of exciting lectures, the latest clinical and preclinical findings…
View Post 5 min This content is machine translated Long Covid With holistic treatment and patience back to normal everyday life Even after a mild covid infection, prolonged symptoms can occur that significantly limit those affected. There are an increasing number of clinical facilities that offer specialized consultations and programs. The…
View Post 4 min This content is machine translated Upper respiratory tract comorbidities When asthma and rhinosinusitis go hand in hand Almost half (45%) of all patients with – mainly severe – asthma are also affected by chronic rhinosinusitis with nasal polyps (CRSwNP). As many as 60% have allergic rhinitis as a…
View Post 3 min This content is machine translated Chronic pain Identification of molecular mechanisms An epigenetic factor known as HDAC4 contributes to the development of chronic pain, as does an organic anion transporter (OAT1). The underlying molecular mechanism has been identified by a team…
