This content is machine translated Psoriasis What is the role of the IL23/Th17 pathway in cardiovascular comorbidities? The IL23/Th17 axis plays an important role in the pathophysiology of psoriasis. A growing body of evidence suggests that inflammatory processes are involved in many cardiovascular and metabolic diseases associated…
View Post 5 min This content is machine translated Chronic inflammatory bowel disease (CED) Clinical nutrition therapy in Crohn’s disease and ulcerative colitis – an update. According to the newly issued ESPEN guidelines, enteral nutrition measures should generally be preferred to parenteral nutrition. There are some exceptions, however, and these include contraindications such as bowel obstruction,…
View Post 3 min This content is machine translated Head and Neck Tumors Salivary gland carcinomas: basic principles and pharmacologic interventions. Salivary gland carcinomas are a rare form of malignancy, however, with high heterogeneity. Therefore, molecular profiling should be used for therapy stratification. Depending on the subentity, different pharmacological interventions may…
View Post 3 min This content is machine translated Benign prostatic hyperplasia Phytotherapeutic combination preparation inhibits inflammation and reduces tissue growth Several clinical studies support the efficacy of a phytopharmacologic sabal/urica combination for the treatment of obstructive and irritative lower urinary tract symptoms (LUTS) in the setting of benign prostatic hyperplasia.…
View Post 5 min This content is machine translated International congresses AAD 2020: selected highlights at a glance In addition to non-steroidal topical therapy alternatives from the field of “small molecules” for the indication areas psoriasis and atopic dermatitis, significant progress has also been made with regard to…
View Post 5 min This content is machine translated Ovarian tumors Of PARP inhibitors, new agents and sexuality The treatment of ovarian cancer is in a constant state of flux with the ongoing development of new drugs such as PARP inhibitors. With increasing experience in the use of…
View Post 5 min This content is machine translated Psoriatic arthritis therapy The search for the best strategy Classic evidence-based recommendations for the treatment of psoriatic arthritis often prove difficult. The reason: Due to the strong heterogeneity of the disease and the study designs often borrowed from RA,…
View Post 2 min This content is machine translated Migraine prophylaxis Erenumab shows good results compared to topiramate Migraine prophylaxis with CGRP antibodies is characterized above all by a rapid onset of action and good tolerability. A phase IV comparative study evaluated erenumab against the anticonvulsant topiramate in…
View Post 4 min This content is machine translated Biomarkers and immunotherapy New horizons in advanced prostate cancer Metastatic castration-resistant prostate cancer (mCRPC) has been considered primarily the domain of novel hormone and taxane therapy. Increasingly, however, other treatment approaches are being tested with sometimes promising results. In…
View Post 5 min This content is machine translated Moderate and severe plaque psoriasis From Immunopathogenesis to Highly Effective Therapies – Enduring Lesion Freedom as the Goal Translational approaches have revolutionized the treatment options for psoriasis. New findings in the field of epidermal immunopathology form the basis for the optimization of highly effective substances. The new generation…
View Post 2 min This content is machine translated Heart failure SGLT2 inhibitors improve cardiovascular risk SGLT2 inhibitors are used with great success as antidiabetic agents. However, new study data revealed a positive side effect: the drug group appears to have additional cardioprotective as well as…