This content is machine translated COPD - current studies The niche for LABA/ICS is getting narrower and narrower The Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommendations regarding initial pharmacotherapy for COPD patients remain unchanged in their 2021 update. However, that could soon change. Current studies suggest:…
View Post 3 min This content is machine translated "Small Molecules" for the Treatment of Psoriasis Oral and topical drug candidates score well in studies As in today’s era of personalized medicine a treatment tailored to the individual needs of psoriasis patients is important, there are several arguments for a use of small molecule substances.…
View Post 3 min This content is machine translated Apremilast Effective reduction of itching in the context of scalp psoriasis Visible pruritic lesions on the scalp are a major stress factor for many psoriasis patients. Topical preparations are used as first-line therapy, but these are not always effective, especially in…
View Post 3 min This content is machine translated Phase IIa study Tocilizumab for the treatment of Schnitzler syndrome Schnitzler syndrome is a rare autoinflammatory disorder. Core symptoms include chronic, recurrent hives. In particular, for patients who do not respond to anti-IL1 therapy, there is a need for new…
View Post 5 min This content is machine translated Dust mite allergy Tiny components with a big impact Dust mite allergy is characterized by year-round symptoms of the nose, lungs and/or eyes. Inadequate diagnosis and treatment may favor the development of allergic asthma (“floor change”). If symptomatic therapy…
View Post 4 min This content is machine translated Blood pressure reduction How low for over 80s and frailty? In antihypertensive therapy in the 80-plus age group, it is important to weigh risk and benefit individually and not to treat strictly according to target values. Frailty (“frailness”) is an…
View Post 5 min This content is machine translated Psoriatic Arthritis New long-term data on guselkumab published Phase III data on the IL23p19 inhibitor guselkumab demonstrate complete resolution of skin symptoms and positive joint effects in adult patients with active psoriatic arthritis (PsoA) lasting over two years.
View Post 4 min This content is machine translated Sublingual immunotherapy New pill against the mite The past year has not brought much news in terms of large studies on sublingual immunotherapy (SLIT) that are suitable for approval. There were new findings, particularly on the effect…
View Post 4 min This content is machine translated Breast Cancer Metastatic pathways in focus Surgical or radiotherapeutic treatment of regional lymph nodes prolongs breast cancer survival and reduces the likelihood of distant metastasis. However, the effect on regional lymph node recurrence appears to be…
View Post 3 min This content is machine translated Studies in focus Interleukin-31 as a clinical target in prurigo nodularis. For the treatment of prurigo nodularis, there are rather few approved therapeutic options available today. There is a need for new effective and well-tolerated treatment options. The use of the…
View Post 28 min This content is machine translated Long-term sequelae of chronic neonatal lung disease. Early changes and later indicators As the most common chronic lung disease in infants, bronchopulmonary dysplasia (BPD) is associated with long-term sequelae that extend into adulthood. Despite significant improvements in perinatal care, the incidence of… CME-Test