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Studies

2524 posts
  • This content is machine translated Personalized PsA therapy

Psoriatic arthritis criterion-guided treatment

An overarching principle for therapy selection in psoriatic arthritis is shared decision making with patients. The GRAPPA recommendations propose an individualized treatment approach that takes into account the predominant disease…
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  • 10 min
  • This content is machine translated Chemo in hospice?

Systems therapies for metastatic NSCLC in poor general health.

Non-small cell lung cancer (NSCLC) is the cancer with the highest mortality worldwide, with two-thirds of cases detected only at locally advanced or metastatic stages. Unfortunately, recommendations for patients with…
CME-Test
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  • 6 min
  • This content is machine translated Multiple sclerosis

Diroximelfumarate impresses with improved gastrointestinal tolerability [1,2]

Diroximel fumarate/DRF is a novel oral fumarate for patients with relapsing-remitting multiple sclerosis (RRMS) that was granted health insurance approval in Switzerland on November 1, 2021, and has been available…
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  • 8 min
  • This content is machine translated Arterial hypertension

Treatment in elderly and frail patients – a challenge

Treatment of arterial hypertension in elderly and frail patients presents challenges at many levels. Because they tend to be at increased risk for adverse effects, medication should be started cautiously.…
CME-Test
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  • 3 min
  • This content is machine translated Lung cancer

New approach to predicting the response of immunotherapies

At Tübingen University Hospital, a preclinical study led by Dr. Clemens Hinterleitner and Prof. Dr. Lars Zender, Medical Director of Medical Oncology and Pneumology, led to extremely promising results. The…
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  • 3 min
  • This content is machine translated Glimmer of hope in the pandemic

Protein ZAP inhibits proliferation of SARS-CoV-2 by 20-fold

Scientists at the Würzburg-based Helmholtz Institute for RNA-based Infection Research (HIRI) and the Helmholtz Centre for Infection Research (HZI) in Braunschweig demonstrate for the first time how ZAP, a protein…
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  • 5 min
  • This content is machine translated Iron deficiency

Classify laboratory parameters correctly

Iron is a trace element that is mainly involved in oxygen transport and blood formation in the body. Both iron deficiency and iron excess can severely disrupt the organism and…
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  • 8 min
  • This content is machine translated Throat infection

Acute tonsillopharyngitis

Upper respiratory tract infections are a common reason for consultation in family practice. Although the recommendation not to prescribe antibiotics for uncomplicated upper respiratory infections made Smarter Medicine’s top 5…
CME-Test
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  • 3 min
  • This content is machine translated Primary hyperaldosteronism

Therapy-resistant hypertension: clarify for Conn syndrome!

If high blood pressure cannot be adequately controlled despite antihypertensive drugs, this may be due to undetected hormonal causes. Hypertension due to primary hyperaldosteronism, also known as “Conn syndrome,” is…
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  • 3 min
  • This content is machine translated Psoriatic arthritis (PsoA)

Pooled analysis on the efficacy of secukinumab from four phase III studies

Improvement in clinical endpoints was seen with secukinumab treatment regardless of latency since initial psoriatic arthritis diagnosis, with patients diagnosed less than one year ago showing a slightly better response…
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  • 5 min
  • This content is machine translated Immunotherapy

Untapped potential in early disease stages

Over the last decade, immunotherapy using checkpoint inhibitors has become established in the treatment of many oncological conditions. Especially in advanced tumor disease, ipilimumab, nivolumab and co. play a significant…

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