This content is machine translated Hypertension Uncontrolled hypertension in the elderly: dose increase or another drug? If the target blood pressure is not achieved, there are two approaches to intensify antihypertensive treatment: adding a new drug or maximizing the dose. A large-scale cohort study involving researchers from…
View Post 12 min This content is machine translated Malignant melanoma Adjuvant Therapy: State of the Art The annual incidence of malignant melanoma has steadily increased over the past 40 years. While the prognosis is good in the early stages, it worsens as the tumor stage increases.… CME-Test
View Post 11 min This content is machine translated Therapy of rheumatoid arthritis Long-term safety for RA patients under JAK inhibition The treatment of rheumatoid arthritis (RA) has made great progress over the past 20 years. This relates both to the range of drugs available and to developments in terms of… CME-Test
View Post 4 min This content is machine translated Psoriatic arthritis (PsA) Guselkumab in joint involvement – successful interim results Long-term data from the pivotal DISCOVER-2 study show that treatment with guselkumab resulted in sustained improvements in joint and skin symptoms and functional capacity over a two-year period in biologic-naïve…
View Post 15 min This content is machine translated Asthma therapy The mild bronchial asthma Bronchial asthma is a heterogeneous, multifactorial disease characterized by chronic airway inflammation and bronchial hyperresponsiveness. Not only the symptomatology, but also the airway obstruction is variable in time course and…
View Post 4 min This content is machine translated Methylphenidate Treatment of apathy in Alzheimer’s disease To date, there is no causal therapy for Alzheimer’s dementia approved in Europe. This makes the treatment of accompanying symptoms all the more important. Here, the focus is particularly on…
View Post 4 min This content is machine translated Voice frequency modulation Alexa, am I getting Parkinson’s? Various disease-modifying therapies for Parkinson’s disease are expected in the coming years, but it is already known: These therapies probably only have the potential to halt the progression of the…
View Post 27 min This content is machine translated Schizophrenia Partial D2 dopamine agonists: pharmacology and clinical significance. Schizophrenia is characterized, among other things, by dopaminergic dysregulation. All antipsychotics approved for their treatment are antagonists of dopamine receptors, particularly D2 and D3 receptors. The three partial D2 dopamine… CME-Test
View Post 4 min This content is machine translated Personalized PsA therapy Psoriatic arthritis criterion-guided treatment An overarching principle for therapy selection in psoriatic arthritis is shared decision making with patients. The GRAPPA recommendations propose an individualized treatment approach that takes into account the predominant disease…
View Post 10 min This content is machine translated Chemo in hospice? Systems therapies for metastatic NSCLC in poor general health. Non-small cell lung cancer (NSCLC) is the cancer with the highest mortality worldwide, with two-thirds of cases detected only at locally advanced or metastatic stages. Unfortunately, recommendations for patients with… CME-Test
View Post 6 min This content is machine translated Multiple sclerosis Diroximelfumarate impresses with improved gastrointestinal tolerability [1,2] Diroximel fumarate/DRF is a novel oral fumarate for patients with relapsing-remitting multiple sclerosis (RRMS) that was granted health insurance approval in Switzerland on November 1, 2021, and has been available…