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Studies

2543 posts
  • This content is machine translated Hypertension

Uncontrolled hypertension in the elderly: dose increase or another drug?

If the target blood pressure is not achieved, there are two approaches to intensify antihypertensive treatment: adding a new drug or maximizing the dose. A large-scale cohort study involving researchers from…
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  • 12 min
  • This content is machine translated Malignant melanoma

Adjuvant Therapy: State of the Art

The annual incidence of malignant melanoma has steadily increased over the past 40 years. While the prognosis is good in the early stages, it worsens as the tumor stage increases.…
CME-Test
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  • 11 min
  • This content is machine translated Therapy of rheumatoid arthritis

Long-term safety for RA patients under JAK inhibition

The treatment of rheumatoid arthritis (RA) has made great progress over the past 20 years. This relates both to the range of drugs available and to developments in terms of…
CME-Test
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  • 4 min
  • This content is machine translated Psoriatic arthritis (PsA)

Guselkumab in joint involvement – successful interim results

Long-term data from the pivotal DISCOVER-2 study show that treatment with guselkumab resulted in sustained improvements in joint and skin symptoms and functional capacity over a two-year period in biologic-naïve…
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  • 15 min
  • This content is machine translated Asthma therapy

The mild bronchial asthma

Bronchial asthma is a heterogeneous, multifactorial disease characterized by chronic airway inflammation and bronchial hyperresponsiveness. Not only the symptomatology, but also the airway obstruction is variable in time course and…
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  • 4 min
  • This content is machine translated Methylphenidate

Treatment of apathy in Alzheimer’s disease

To date, there is no causal therapy for Alzheimer’s dementia approved in Europe. This makes the treatment of accompanying symptoms all the more important. Here, the focus is particularly on…
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  • 4 min
  • This content is machine translated Voice frequency modulation

Alexa, am I getting Parkinson’s?

Various disease-modifying therapies for Parkinson’s disease are expected in the coming years, but it is already known: These therapies probably only have the potential to halt the progression of the…
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  • 27 min
  • This content is machine translated Schizophrenia

Partial D2 dopamine agonists: pharmacology and clinical significance.

Schizophrenia is characterized, among other things, by dopaminergic dysregulation. All antipsychotics approved for their treatment are antagonists of dopamine receptors, particularly D2 and D3 receptors. The three partial D2 dopamine…
CME-Test
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  • 4 min
  • This content is machine translated Personalized PsA therapy

Psoriatic arthritis criterion-guided treatment

An overarching principle for therapy selection in psoriatic arthritis is shared decision making with patients. The GRAPPA recommendations propose an individualized treatment approach that takes into account the predominant disease…
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  • 10 min
  • This content is machine translated Chemo in hospice?

Systems therapies for metastatic NSCLC in poor general health.

Non-small cell lung cancer (NSCLC) is the cancer with the highest mortality worldwide, with two-thirds of cases detected only at locally advanced or metastatic stages. Unfortunately, recommendations for patients with…
CME-Test
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  • 6 min
  • This content is machine translated Multiple sclerosis

Diroximelfumarate impresses with improved gastrointestinal tolerability [1,2]

Diroximel fumarate/DRF is a novel oral fumarate for patients with relapsing-remitting multiple sclerosis (RRMS) that was granted health insurance approval in Switzerland on November 1, 2021, and has been available…

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