This content is machine translated Atopic dermatitis JAK inhibition as a mode of action – an update. Janus kinase (JAK) inhibitors are a promising new treatment option for adult patients with atopic eczema, given their rapid relief of pruritus and inflammatory lesions. In addition to baricitinib, which…
View Post 9 min This content is machine translated Treatment of relatives Family members and close relatives as patients Physicians are often asked by relatives and acquaintances for opinions, assessments and treatments. In doing so, however, they often enter an ethical gray area insidiously and unnoticed. The transition from… CME-Test
View Post 4 min This content is machine translated COPD - current studies The niche for LABA/ICS is getting narrower and narrower The Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommendations regarding initial pharmacotherapy for COPD patients remain unchanged in their 2021 update. However, that could soon change. Current studies suggest:…
View Post 3 min This content is machine translated "Small Molecules" for the Treatment of Psoriasis Oral and topical drug candidates score well in studies As in today’s era of personalized medicine a treatment tailored to the individual needs of psoriasis patients is important, there are several arguments for a use of small molecule substances.…
View Post 3 min This content is machine translated Apremilast Effective reduction of itching in the context of scalp psoriasis Visible pruritic lesions on the scalp are a major stress factor for many psoriasis patients. Topical preparations are used as first-line therapy, but these are not always effective, especially in…
View Post 3 min This content is machine translated Phase IIa study Tocilizumab for the treatment of Schnitzler syndrome Schnitzler syndrome is a rare autoinflammatory disorder. Core symptoms include chronic, recurrent hives. In particular, for patients who do not respond to anti-IL1 therapy, there is a need for new…
View Post 5 min This content is machine translated Dust mite allergy Tiny components with a big impact Dust mite allergy is characterized by year-round symptoms of the nose, lungs and/or eyes. Inadequate diagnosis and treatment may favor the development of allergic asthma (“floor change”). If symptomatic therapy…
View Post 4 min This content is machine translated Blood pressure reduction How low for over 80s and frailty? In antihypertensive therapy in the 80-plus age group, it is important to weigh risk and benefit individually and not to treat strictly according to target values. Frailty (“frailness”) is an…
View Post 5 min This content is machine translated Psoriatic Arthritis New long-term data on guselkumab published Phase III data on the IL23p19 inhibitor guselkumab demonstrate complete resolution of skin symptoms and positive joint effects in adult patients with active psoriatic arthritis (PsoA) lasting over two years.
View Post 4 min This content is machine translated Sublingual immunotherapy New pill against the mite The past year has not brought much news in terms of large studies on sublingual immunotherapy (SLIT) that are suitable for approval. There were new findings, particularly on the effect…
View Post 4 min This content is machine translated Breast Cancer Metastatic pathways in focus Surgical or radiotherapeutic treatment of regional lymph nodes prolongs breast cancer survival and reduces the likelihood of distant metastasis. However, the effect on regional lymph node recurrence appears to be…
