This content is machine translated Severe eosinophilic asthma Small airways as a predictor of biologics Biologic anti-T2 therapies can effectively reduce acute exacerbations and the need for daily doses of oral steroids in severe eosinophilic asthma. However, expiratory flow (FEV1) benefits little and shows only…
View Post 4 min This content is machine translated Psoriasis infestation of scalp, nails and palmoplantar Excellent long-term data – IL23 inhibitor improves symptoms and quality of life Psoriasis in highly visible locations is particularly stigmatizing for patients. There is a high demand for effective and safe treatment options, especially for severe forms of the disease. Of those…
View Post 15 min This content is machine translated Malnutrition A lightweight with heavyweight The European Society for Clinical Nutrition and Metabolism (ESPEN) defines ME as a nutritional state in which energy, protein, and micronutrient deficiencies result in altered body composition (decreased muscle mass)… CME-Test
View Post 3 min This content is machine translated Advanced malignant melanoma Adjuvant immunotherapy with nivolumab: promising long-term results According to current study data, more than half of the patients who received adjuvant treatment with the anti-PD-1 antibody were relapse-free after four years. This is further confirmation of the…
View Post 3 min This content is machine translated Coronary heart disease (CHD) Innovative method for non-invasive diagnostics in suspected CHD cases. When coronary heart disease (CHD) is suspected, the question arises as to how the family physician should best proceed diagnostically. There is a need for optimization of noninvasive CHD diagnostics…
View Post 3 min This content is machine translated Vitamin supplementation COVID-19 and vitamin D: sticking to the facts Recent scientific publications have brought back into focus the debate on a possible protective role of vitamin D supplementation for severe COVID-19 progression. When interpreting the study findings, however, it…
View Post 4 min This content is machine translated Obesity Goodbye prosperity belly – welcome feel-good weight! The proportion of severely overweight or obese patients is steadily increasing. The common disease is seen more of a health disorder resulting from an unhealthy lifestyle. However, the consequences can…
View Post 4 min This content is machine translated Small Molecules Phosphodiesterase-4 as a therapeutic target in psoriasis – an update. The oral PDE-4 inhibitor apremilast has been an established treatment option for moderate to severe chronic plaque psoriasis and psoriatic arthritis for several years. And in a phase IIb study…
View Post 4 min This content is machine translated Anxiety and sleep disorders Phytotherapeutic agent has no effect on driving ability Anxiety and sleep disorders are common and are associated with a reduced quality of life. Sedatives such as benzodiazepines have anxiolytic effects but impair driving ability. This is associated with…
View Post 6 min This content is machine translated Diabetes mellitus Biomarker-associated clustering for improved treatment management. Phenotyping and subclassification of diabetic patients is becoming increasingly important to provide patient-adapted treatment options. Meanwhile, there are several cluster analyses that could reveal certain specific patterns of patient characteristics.…
View Post 7 min This content is machine translated Urothelial carcinoma The role of checkpoint inhibitors Immunotherapy is also becoming increasingly important in the treatment of urothelial carcinoma. Checkpoint inhibitors are already being used successfully, particularly in advanced tumors. Now, potential applications of avelumab, atezolizumab and…
