This content is machine translated Migraine prevention Erenumab effective and safe in the long term in clinical practice Recent trial data strengthen the role of erenumab as a preventive migraine treatment. They confirm the real and long-term benefits of the CGRP inhibitor in terms of safety and efficacy…
View Post 3 min This content is machine translated Non-small cell lung cancer and other solid tumors In the pipeline: KRAS G12C inhibitor Sotorasib The KRAS gene is one of the most frequently mutated oncogenes in human cancers and thus represents a promising target in the therapy of diverse solid tumors. Sotorasib is currently…
View Post 3 min This content is machine translated GLP-1 receptor agonists in type 2 diabetes Nephroprotection with semaglutide and liraglutide – direct or indirect effects? In a post-hoc analysis of large randomized placebo-controlled trials, HbA1c and body weight and blood pressure were examined as mediator variables regarding the renal protective effects of the GLP-1 receptor…
View Post 3 min This content is machine translated Diabetic ketoacidosis Study: ketoacidosis in infancy affects brain development Diabetic ketoacidosis (DKA) can have consequences for a child’s brain, an American research group shows in the journal Diabetes Care. The German Diabetes Society (DDG) points out the need to…
View Post 3 min This content is machine translated Myeloid diseases New trends in the treatment of acute myeloid leukemia Understanding about myeloid diseases, such as acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS), is becoming more concrete thanks to intensive research. Recent study results have shown that there is…
View Post 1 min This content is machine translated Corona pandemic EMA reviews first COVID-19 vaccine candidate AZD1222, a vaccine developed by AstraZeneca in collaboration with the University of Oxford, is under rolling review by the Committee for Medicinal Products for Human Use of the European Medicines…
View Post 3 min This content is machine translated Acute pulmonary embolism Surprising results on mortality from thrombosis and pulmonary embolism. The Center for Thrombosis and Hemostasis (CTH) at the University Medical Center Mainz has published study results in Lancet Respiratory Medicine: a decreasing death rate due to pulmonary embolism was…
View Post 2 min This content is machine translated Heinz Nixdorf Recall Study When the heart vessels calcify – susceptibility also hereditary An interdisciplinary research team from the Medical Faculty of the University of Duisburg-Essen (UDE) has been able to prove that a person’s lifestyle is not the only factor responsible for…
View Post 6 min This content is machine translated Anorexia nervosa The role of the family doctor Family physicians are often the first point of contact for patients with eating disorders. Targeted screening questions based on the diagnostic criteria can be an aid in recognizing anorectic symptomatology…
View Post 9 min This content is machine translated Rare lung diseases Granulomatoses beyond sarcoidosis: the rheumatologic view. Pulmonary involvement in the setting of inflammatory rheumatic systemic disease is a relatively common manifestation that requires appropriate awareness by both pulmonologists and rheumatologists and, ideally, interdisciplinary management of such…
View Post 4 min This content is machine translated Diabetic nephropathy SGLT-2 inhibitor slows decline in glomerular filtration rate For the first time, a targeted therapy for diabetic kidney disease is available. In the CREDENCE study, canagliflozin resulted in a clinically relevant and statistically significant risk reduction for renal…
