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Studies

2301 posts
  • This content is machine translated What biomarkers reveal about "biological youth" - and what not (yet)

Epigenetic ageing

In recent years, epigenetic clocks based on DNA methylation have evolved from research tools to widely used biomarkers of biological ageing. They correlate not only with chronological age, but also...…
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  • 10 min
  • This content is machine translated Mechanisms, evidence and therapeutic consequences

GLP-1 receptor agonists in cardiology

GLP-1 receptor agonists (GLP-1RAs) have rapidly evolved from antidiabetic drugs to cardiometabolic therapies with clinically proven reductions in hard cardiovascular endpoints – and increasingly beyond the traditional diabetes population. The...…
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  • 6 min
  • This content is machine translated MASLD/MASH

Drug therapy options on the rise: spectacular evidence

Over the last few decades, the incidence of steatotic liver disease has risen in parallel with the increase in obesity, diabetes and other metabolic diseases. It is recommended to screen...…
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  • 6 min
  • This content is machine translated New ways of neuroregeneration

CRISPR and artificial intelligence

The combination of precise genome editing using CRISPR and AI-supported modeling of complex CNS damage marks a paradigm shift in neuroregeneration. Adaptive, closed therapy loops are designed to address multiple...…
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  • 7 min
  • This content is machine translated Focus on new therapeutic targets and senolytics

Cellular senescence

Cellular senescence is considered a key biological program that can exert both protective and potentially pathogenic effects in tissues across the lifespan. If senescent cells persist, they are associated with...…
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  • 32 min
  • This content is machine translated Music as a cure for cancer?

Music therapy in Swiss oncology

Music therapy is becoming increasingly important as part of integrative treatment approaches and complementary procedures in cancer treatment. The workshop held by a music therapist from Inselspital Bern at this...…
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  • 7 min
  • This content is machine translated Arterial elasticity, vascular ageing, endothelial function

Longevity and cardiovascular health 2025

Vascular ageing is not a purely “biological” concept, but can be measured clinically – via arterial stiffness (e.g. PWV), endothelial function (e.g. FMD) and the resulting risk profiles. In parallel...…
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  • 8 min
  • This content is machine translated Clinical significance, pathophysiology, diagnosis and management

Frailty in COPD

Frailty has established itself as a central concept in modern pulmonology in recent years. While the syndrome was originally described primarily as a geriatric phenomenon, more recent data shows that...…
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  • 5 min
  • This content is machine translated Bladder infections and urinary tract infections

Survey reveals information deficits in the population

A recently published survey conducted on the initiative of the European Association of Urology revealed worrying gaps in knowledge and misunderstandings regarding the prevention and treatment of cystitis and urinary...…
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  • 6 min
  • This content is machine translated Hormone balance and longevity

Ageing is not a substitution diagnosis

In the longevity debate, “hormone balance” is often used as a synonym for “biologically younger”. Clinically, the term is only meaningful if it is linked to clearly defined axial disorders,...…
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  • 4 min
  • This content is machine translated Early detection of type 1 diabetes

Detection of insulin autoantibodies as an early marker

Type 1 diabetes develops in several stages, whereby in the first preclinical phase only diabetes-specific autoantibodies are initially present in the blood, but the patients are normoglycaemic. Targeted screening is...…

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