This content is machine translated Psoriasis and Obesity: Effects of Incretin-Based Therapies Clinical trials shed light on the potential of semaglutide, liraglutide, and tirzepatide The bidirectional relationship between psoriasis and obesity is supported by a growing body of evidence, and it is now known that there are common inflammatory pathways. Current studies are investigating...…
View Post 4 min This content is machine translated Non-small-cell lung cancer (NSCLC) Long-term data from the CROWN study: Efficacy and intracranial control Updated 7-year data from the CROWN study were presented at the 2026 ASCO Annual Meeting. These data confirm stable long-term disease control with lorlatinib and reinforce its role as a...…
View Post 6 min This content is machine translated Malignant oral squamous cell carcinomas (OPSCC/HNSCC) Innovative Treatment Options The latest data from the AREST study, presented at the 2026 ASCO Annual Meeting, demonstrate that adjuvant radiation therapy following curative surgery for early-stage oral squamous cell carcinoma significantly improves...…
View Post 3 min This content is machine translated Advanced solid tumors Survival Plateaus with Botensilimab + Balstilimab At the 2025 ESMO Congress, a wealth of data on solid tumors was presented. This included an updated analysis of the combination of botensilimab and balstilimab.... Dieser Inhalt ist nur…
View Post 7 min This content is machine translated Eosinophils in the Blood in COPD How many measurements are needed to be sure? Approximately 20–40% of all COPD patients exhibit Type 2 inflammation, which is characterized by elevated BEC. This eosinophilic phenotype is associated with an increased risk of exacerbations and a favorable...…
View Post 6 min This content is machine translated Soft-tissue sarcomas of the upper extremities Immunotherapy and Molecular Targets New immunotherapy strategies for soft tissue sarcomas were presented at the 2026 ASCO Annual Meeting. The focus was on biomarker-based approaches using pembrolizumab and PD-L1 inhibition, which are also gaining...…
View Post 6 min This content is machine translated C3 glomerulopathy—can its progression be halted? Iptacopan and Pegcetacoplan Open Up New Horizons To diagnose C3 glomerulopathy (C3G) and distinguish it from other membranoproliferative glomerulopathies, a kidney biopsy is required in addition to measuring the concentration of the complement protein C3 in the...…
View Post 6 min This content is machine translated CKD: Cardiorenal Benefits of nsMRA and GLP-1RA FIND-CKD and FLOW: Benefits Across Heterogeneous Patient Populations Finerenon significantly slowed the decline in kidney function in non-diabetic adults with chronic kidney disease (CKD) and also reduced the risk of cardiovascular complications —according to recently published data from...…
View Post 8 min This content is machine translated IgA Nephropathy: The Evolving Landscape of Treatment What are the most important game-changers? IgA nephropathy, also known as “Berger’s disease,” is the most common form of glomerulonephritis worldwide. It is an immune-mediated kidney disease diagnosed based on urine test results and a kidney...…
This content is machine translated Chronic Lymphocytic Leukemia (CLL) Personalized Therapy in the Age of Targeted Drugs New data on the use of pirtobrutinib in treatment-naive patients with chronic lymphocytic leukemia were presented at the 2026 ASCO Annual Meeting. The results from the Phase 3 studies BRUIN...…
View Post 3 min This content is machine translated HGSOC PARP-based, molecular, and immunological therapeutic approaches At ASCO 2026, various therapeutic approaches for high-grade serous ovarian cancer (HGSOC) were presented. These included current data on genome-wide HRD characterization in the context of PARP maintenance therapy and...…
