This content is machine translated Irritable Bowel Syndrome IBS or endometriosis? Chronic pelvic pain ( CPP) is a common reason for referral to gynecology departments and is commonly attributed to endometriosis. However, gastrointestinal disorders, particularly irritable bowel syndrome (IBS), have several...…
View Post 4 min This content is machine translated MASH Pharmacotherapies as “Game Changers”—What Are the Upcoming Challenges? Two drug therapy options—semaglutide (s.c.) and resmetirom (oral)—are now approved in the EU and the U.S. for the treatment of MASH. This is a major breakthrough, especially since, for a...…
View Post 4 min This content is machine translated Cholangiocarcinoma Modern molecular diagnostics and targeted therapy options Cholangiocarcinoma (CCA) is one of the most aggressive tumors of the hepatobiliary system and is often only diagnosed at an advanced stage. Advances in molecular diagnostics and targeted therapy are...…
View Post 6 min This content is machine translated Treatment resistant depression Esketamine nasal spray as monotherapy? New for treatment-resistant depression Despite a variety of approved antidepressant treatments, major depressive disorder (MDD) remains one of the leading causes of disability worldwide and has been shown to shorten the life expectancy of...…
View Post 7 min This content is machine translated Actinic keratoses Targeted Treatment of Multiple AK Lesions—Balancing Efficacy and Convenience Actinic keratoses occur singly or in confluent patches on sun-exposed areas of the skin. Clinical and/or dermatoscopic diagnosis can be supported by non-invasive diagnostic tools such as confocal microscopy and...…
View Post 4 min This content is machine translated Tuberculosis Detecting diabetes in TB patients early and efficiently People with diabetes have a significantly increased risk of tuberculosis and poorer treatment outcomes, which is why systematic diabetes screening is recommended for TB patients. A meta-analysis showed that previously...…
View Post 4 min This content is machine translated Trichophyton indotineae Terbinafine-resistant dermatophytoses are on the rise in Central Europe Trichophyton indotineae (T. indotineae) often causes persistent, recurrent skin infections and is spreading worldwide. The fact that the number of cases has also increased in Central Europe in recent years...…
View Post 7 min This content is machine translated Disease-modifying therapies for ATTR-CM TTR stabilizers, gene silencing and gene scissors: where do we stand? Advances in the understanding of the pathophysiology of transthyretin amyloid cardiomyopathy (ATTR-CM) have revolutionized the therapeutic landscape in recent years. TTR stabilizers such as tafamidis and acoramidis can reduce TTR...…
View Post 8 min This content is machine translated Proteins in wound healing Do special amino acids lead to success? Wound healing is a complex process. Depending on which wound healing phase you are in, a wide variety of mediators are involved. A finely tuned combination of all basic nutrients...… CME-Test
View Post 4 min This content is machine translated HER2+ early breast cancer DESTINY-Breast11 – neoadjuvant T-DXd without anthracyclines The phase III DESTINY-Breast11 trial shows that neoadjuvant trastuzumab deruxtecan (T-DXd) could provide an anthracycline-free treatment option for HER2-positive early breast cancer. The results suggest an effective and better tolerated...…
View Post 3 min This content is machine translated Lavender aromatherapy Take away the fear of the dentist Fear of the dentist is still widespread and often leads to avoidance of treatment and a resulting deterioration in oral health. Supplementary non-pharmacological measures are increasingly being used to make...…