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Studies

2520 posts
  • This content is machine translated MASH

Pharmacotherapies as “Game Changers”—What Are the Upcoming Challenges?

Two drug therapy options—semaglutide (s.c.) and resmetirom (oral)—are now approved in the EU and the U.S. for the treatment of MASH. This is a major breakthrough, especially since, for a...…
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  • 13 min
  • This content is machine translated Obesity Treatment

Oral GLP-1 Therapies: ATTAIN-1 and OASIS-4—The Next Leap Forward

Injectable GLP-1 receptor agonists and the dual GIP/GLP-1 agonist tirzepatide have redefined pharmacological obesity treatment and achieved weight loss in the range of 15 to 20% in clinical trials. Nevertheless,...…
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  • 5 min
  • This content is machine translated Older patients with atopic dermatitis

Why the Use of Biologics Is Recommended

In light of demographic trends, an increase in the prevalence of atopic dermatitis is also being observed among the elderly population. Tailored treatment plans take into account a wide range...…
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  • 4 min
  • This content is machine translated Disorders of the Gut-Brain Interaction

Peppermint-Caraway Oil Supplement Proves Effective in Phase IV Trial

In primary care , disorders of the gut-brain axis—also known as functional gastrointestinal disorders—are very common. Herbal remedies, such as a proprietary combination of peppermint oil (Mentha × piperita L.)...…
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  • 5 min
  • This content is machine translated Gepante for Migraines

Relief from pain, symptoms, and improved functional ability—both acute and preventive

Migraine management goes beyond acute symptom control and may also include preventive strategies for patients with a significant disease burden. Although triptans remain the recommended first-line treatment for acute migraine,...…
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  • 12 min
  • This content is machine translated Why the Finerenon Boom Is Giving Hyperkalemia Treatment New Relevance

Potassium binders as enablers of RAASi optimization

Renin-angiotensin-aldosterone system (RAAS) inhibitors—including mineralocorticoid receptor antagonists (MRAs)—are among the most effective tools in cardiorenal medicine. However, their benefits are often undermined in everyday clinical practice because fear of hyperkalemia...…
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  • 3 min
  • This content is machine translated Asthma in Adults: Bronchodilation and Anti-Inflammatory Therapy

Remodeling can be counteracted through a proactive treatment strategy

If certain key, evidence-based principles are followed, remission is now an achievable goal in asthma treatment. First, it is recommended to routinely supplement spirometry with a blood test to measure...…
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  • 12 min
  • This content is machine translated SURPASS-CVOT

Tirzepatide versus Dulaglutide in T2D with ASCVD

GLP-1 receptor agonists have established themselves in recent years as a class of drugs with cardiovascular protective effects in type 2 diabetes. For dulaglutide, the 2019 REWIND study showed that...…
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  • 6 min
  • This content is machine translated Secondary prevention after ACS: individually optimized lipid management

Trend towards early combination therapy and new strategies for lowering Lp(a)

Secondary prevention after an acute coronary syndrome (ACS) is crucial for improving quality of life and reducing morbidity and mortality rates. Elevated blood lipid levels such as LDL cholesterol and...…
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  • 27 min
  • This content is machine translated Pediatric Brain Tumors

Psychiatry versus Neuro-Oncology: Diagnostic Pitfalls

Pediatric brain tumors often begin with nonspecific symptoms—some physical, some behavioral—that can be attributed to internal medicine or psychiatric differential diagnoses, thereby presenting typical diagnostic pitfalls. Clinical case examples from...…
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  • 13 min
  • This content is machine translated What the latest studies on the entire EF spectrum mean for clinical practice

Heart Failure – The 2026 Evidence Update

Since the release of the 2021 ESC guidelines and the 2022 AHA/ACC/HFSA guidelines, research on heart failure has reached a remarkable level of intensity. Nonsteroidal mineralocorticoid receptor antagonists and incretin-based...…

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