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Posts by tag

Dupilumab

37 posts
  • This content is machine translated Chronic pruritus: “Tour d'horizon”

Focus on new anti-inflammatory therapeutic approaches

Chronic pruritus is associated with considerable suffering and can occur both as part of classic dermatoses and as a leading symptom of many internal diseases. In chronic prurigo, long-lasting itching...…
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  • 4 min
  • This content is machine translated Biologics for atopic dermatitis

Th2 cytokines in focus: proven and new targets

The range of antibody therapies for atopic dermatitis (AD) has expanded once again in Europe. In addition to dupilumab and tralokinumab, lebrikizumab is another biologic available in this country that...…
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  • 6 min
  • This content is machine translated Atopic dermatitis

Biologics and JAK-i – the best of both worlds

In Switzerland, both the currently approved monoclonal antibodies (dupilumab, tralokinumab, lebrikizumab) and the Janus kinase (JAK) inhibitors (baricitinib, abro-citinib, upadacitinib) can be used as “first-line” systemic therapy for patients with...…
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  • 3 min
  • This content is machine translated COPD therapy

Package of measures to combat symptom complexes – an update

In COPD, dual bronchodilation (LAMA/LABA) is generally considered the standard of care. If patients are prone to exacerbations, the addition of inhaled steroids (ICS) may be useful. But what about...…
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  • 4 min
  • This content is machine translated Asthma: focus on type 2 inflammation

Remission as a new therapeutic goal

A paradigm shift is emerging in the management of asthma, where the aim is not only asthma control but also remission. It has been shown that this ambitious goal can...…
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  • 9 min
  • This content is machine translated Journal Club: Atopic dermatitis

Modern systems therapy – status quo and prospects

The therapeutic landscape for atopic dermatitis is changing. New findings have made it possible to develop modern treatment options that selectively target inflammatory signaling pathways. There are currently two modern…
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  • 6 min
  • This content is machine translated Chronic prurigo

Antipruritic therapy alleviates suffering

Chronic prurigo is associated with persistent papules and nodules on the skin and is now defined as a disease in its own right. However, this was not always the case:…
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  • 7 min
  • This content is machine translated Biologics for AD

Interleukin-13 as a target – new long-term data available

Now that the range of systemic therapeutics for atopic dermatitis has been expanded and the two monoclonal antibodies dupilumab and tralokinumab as well as three Janus kinase inhibitors have been…
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  • 4 min
  • This content is machine translated Dupilumab for COPD and asthma

Exacerbations reduced and lung function improved

The monoclonal antibody dupilumab blocks the common receptor component for interleukin (IL)-4 and IL-13, the central drivers of type 2 inflammation. It has been approved in Switzerland since 2019, and…
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  • 8 min
  • This content is machine translated Atopic dermatitis

Reaching the goal with stage-adapted treatment and patient education

The updated German-language guideline for the treatment of atopic dermatitis (AD) is based on the EuroGuiDerm guideline and has been expanded to include some important new features. Since AD is…
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  • 5 min
  • This content is machine translated Severe asthma

Check diagnosis and initiate phenotype-based therapy

In patients with inadequately controlled asthma under maximum inhalation therapy, it should be critically questioned whether the diagnosis of asthma is really present and whether all treatment measures are being…
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