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Posts by tag

Dupilumab

42 posts
  • This content is machine translated Chronic urticaria: new treatment alternatives in sight

If antihistamines are not sufficient and IgE levels are low

Chronic urticaria often leads to a high level of suffering, but new treatment options are on the way – a lot has happened since the publication of the current S3...…
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  • 5 min
  • This content is machine translated Moderate to severe atopic dermatitis

Established and novel biologics – the therapeutic landscape is in flux

Clinically, atopic dermatitis (AD) manifests itself through a polymorphic picture of efflorescences, with pruritus and xerosis in the foreground. In addition to the antibody therapies dupilumab, tralokinumab and lebrikizumab, which...…
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  • 6 min
  • This content is machine translated COPD: Tailor therapy to individual characteristics

Risk of exacerbation correlates with the eosinophil count and other factors

The severity of COPD is determined based on lung function values, exacerbation history and symptom burden. A triple combination with inhaled steroids (ICS) is recommended for patients with a high...…
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  • 6 min
  • This content is machine translated Atopic dermatitis: proven therapeutic principles and innovations

From healthcare research to precision medicine

In Switzerland, around 20 percent of children are affected by atopic eczema, compared to 4-5 percent of adults. The disease burden of AD is considerable, which is also related to...…
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  • 5 min
  • This content is machine translated Prurigo and PN

Anti-inflammatory antipruritic therapy improves quality of life

Which mediators are causally involved in peripheral and central itch sensitization in the context of prurigo and prurigo nodularis (PN) and contribute to the maintenance of pruritus is currently being...…
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  • 6 min
  • This content is machine translated Chronic pruritus: “Tour d'horizon”

Focus on new anti-inflammatory therapeutic approaches

Chronic pruritus is associated with considerable suffering and can occur both as part of classic dermatoses and as a leading symptom of many internal diseases. In chronic prurigo, long-lasting itching...…
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  • 4 min
  • This content is machine translated Biologics for atopic dermatitis

Th2 cytokines in focus: proven and new targets

The range of antibody therapies for atopic dermatitis (AD) has expanded once again in Europe. In addition to dupilumab and tralokinumab, lebrikizumab is another biologic available in this country that...…
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  • 6 min
  • This content is machine translated Atopic dermatitis

Biologics and JAK-i – the best of both worlds

In Switzerland, both the currently approved monoclonal antibodies (dupilumab, tralokinumab, lebrikizumab) and the Janus kinase (JAK) inhibitors (baricitinib, abro-citinib, upadacitinib) can be used as “first-line” systemic therapy for patients with...…
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  • 3 min
  • This content is machine translated COPD therapy

Package of measures to combat symptom complexes – an update

In COPD, dual bronchodilation (LAMA/LABA) is generally considered the standard of care. If patients are prone to exacerbations, the addition of inhaled steroids (ICS) may be useful. But what about...…
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  • 4 min
  • This content is machine translated Asthma: focus on type 2 inflammation

Remission as a new therapeutic goal

A paradigm shift is emerging in the management of asthma, where the aim is not only asthma control but also remission. It has been shown that this ambitious goal can...…
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  • 9 min
  • This content is machine translated Journal Club: Atopic dermatitis

Modern systems therapy – status quo and prospects

The therapeutic landscape for atopic dermatitis is changing. New findings have made it possible to develop modern treatment options that selectively target inflammatory signaling pathways. There are currently two modern…
  • IBD matters

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