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Allergology and clinical immunology

456 posts
  • This content is machine translated Interview with Prof. Thomas Kündig (USZ)

“If we control itching and eczema, a normal life is possible again”

Atopic dermatitis (AD) continues to pose challenges for dermatology – not least due to its complex immunopathogenesis [1]. In this interview, Prof. Dr. med. Thomas Kündig, University Hospital Zurich, explains...…
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  • 8 min
  • This content is machine translated Psoriasis and PsA

Biologics, oral peptide and trivalent nanobody – current results and trends

Top-line results are available for both Icotrokinra and Sonelokimab, which attest to the great therapeutic potential of these innovative drug candidates. However, there is also extremely interesting new evidence from...…
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  • 6 min
  • This content is machine translated Study report: Hidradenitis suppurativa

Comparison of rifampicin monotherapy with clindamycin/rifampicin combination

In a recent study, the inflammatory correlates in patients with hidradenitis suppurativa (HS) were analyzed before and after oral antibiotic therapy. There is evidence that the efficacy of systemic antibiotics...…
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  • 7 min
  • This content is machine translated Atopic dermatitis and allergies Atopic dermatitis and allergies

Type 2 inflammation and other factors

Atopic patients are prone to immediate-type allergies and many studies show a correlation between sensitization to aeroallergens and exacerbations of atopic dermatitis (AD). A common characteristic of atopic diseases is...…
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  • 6 min
  • This content is machine translated Chronic pruritus: “Tour d'horizon”

Focus on new anti-inflammatory therapeutic approaches

Chronic pruritus is associated with considerable suffering and can occur both as part of classic dermatoses and as a leading symptom of many internal diseases. In chronic prurigo, long-lasting itching...…
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  • 4 min
  • This content is machine translated Work-related asthma

When the job leads to exacerbations

Asthma attacks caused by occupational exposure are very common in adults with asthma. Although previous studies have mainly focused on occupational asthma (OA), interest in work-exacerbated ast hma (WEA) has...…
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  • 7 min
  • This content is machine translated Moderate to severe chronic hand eczema

Delgocitinib cream – first topical pan-JAK inhibitor approved in Switzerland

In the phase III DELTA 1 and 2 studies, delgocitinib cream showed a rapid onset of efficacy – at week 16, half of the patients achieved a 75% improvement in...…
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  • 4 min
  • This content is machine translated Prurigo nodularis

Retrospective analyses of large data sets from everyday practice

Prurigo nodularis (PN) is a chronic inflammatory skin disease that manifests itself as extremely itchy hard nodules. Prof. Dr. med. Dr. rer nat. Enno Schmidt from the University Hospital Schleswig-Holstein...…
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  • 4 min
  • This content is machine translated Oral JAK-i in atopic dermatitis

Benefits and risks: What does the current data say?

Although there have been no recent approvals of oral JAK inhibitors (JAK-i) for atopic dermatitis (AD), some interesting study findings have been published. These shed light on the safety of...…
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  • 4 min
  • This content is machine translated Biologics for atopic dermatitis

Th2 cytokines in focus: proven and new targets

The range of antibody therapies for atopic dermatitis (AD) has expanded once again in Europe. In addition to dupilumab and tralokinumab, lebrikizumab is another biologic available in this country that...…
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  • 7 min
  • This content is machine translated Study report

Scabies treatment: benzyl benzoate in direct comparison with permethrin

European guidelines mention permethrin, benzyl benzoate and crotamiton as topical antiscabiosa. There have been repeated reports of treatment failure with permethrin in recent years, although the causes are controversial. In...…

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