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Allergology and clinical immunology

471 posts
  • This content is machine translated Prurigo nodularis: evidence-based treatment

Targeted therapy options on the rise

The pathophysiology of prurigo nodularis (PN) is multifactorial and complex, but great progress has recently been made in terms of treatment options. In addition to the monoclonal antibodies dupilumab and...…
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  • 5 min
  • This content is machine translated Severe asthma and CRSwNP

Multidisciplinary collaboration between pneumology, allergology and ENT

Severe eosinophilic asthma (SEA) and chronic rhinosinusitis with nasal polyps (CRSwNP) are overlapping clinical entities united by a common pathophysiological basis of type 2 inflammation. The frequent co-occurrence of these...…
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  • 5 min
  • This content is machine translated Seborrheic dermatitis in adults

Do not underestimate the symptom burden

Seborrhoeic eczema is caused by a complex interplay of dysbiosis, impaired skin barrier function and immunological dysregulation. It occurs preferentially in areas rich in sebaceous glands and is associated with...…
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  • 5 min
  • This content is machine translated Moderate to severe atopic dermatitis

Established and novel biologics – the therapeutic landscape is in flux

Clinically, atopic dermatitis (AD) manifests itself through a polymorphic picture of efflorescences, with pruritus and xerosis in the foreground. In addition to the antibody therapies dupilumab, tralokinumab and lebrikizumab, which...…
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  • 4 min
  • This content is machine translated Case series

Mast cell activation syndrome (MCAS)

MCAS is now understood as an independent disorder in contrast to systemic or cutaneous mastocytosis. The signs and symptoms can affect the skin, the gastrointestinal tract and the cardiovascular system,...…
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  • 9 min
  • This content is machine translated Irritable Bowel Syndrome

“Best practice” recommendations for step-by-step clarification and stage-adapted therapy

The diagnosis of irritable bowel syndrome (IBS) is based on the Rome IV criteria for functional gastrointestinal disorders. The main symptoms are abdominal pain and altered bowel habits, but patients...…
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  • 10 min
  • This content is machine translated Contact eczema

Causes and prevention at work

Occupational groups with a high risk of developing occupational eczema include jobs with increased wet work and/or exposure to allergens. Initially, irritant hand eczema typically occurs, which can be a...…
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  • 6 min
  • This content is machine translated Hidradenitis suppurativa: biologics reduce inflammatory processes

Treatment recommendations depend on the severity and inflammatory activity

Due to its phenotypic heterogeneity and multifactorial pathogenesis, hidradenitis suppurativa is a complex disease that can be difficult to treat. Fortunately, research has achieved significant breakthroughs in the recent past,...…
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  • 4 min
  • This content is machine translated Acne treatment: current trends

What role do dermocosmetics play?

Acne vulgaris is characterized by excessive sebum production, inflammation and impaired skin barrier function. Effective treatments should target both lesion reduction and skin hydration while being well tolerated. In this...…
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  • 6 min
  • This content is machine translated Atopic dermatitis: proven therapeutic principles and innovations

From healthcare research to precision medicine

In Switzerland, around 20 percent of children are affected by atopic eczema, compared to 4-5 percent of adults. The disease burden of AD is considerable, which is also related to...…
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  • 5 min
  • This content is machine translated Prurigo and PN

Anti-inflammatory antipruritic therapy improves quality of life

Which mediators are causally involved in peripheral and central itch sensitization in the context of prurigo and prurigo nodularis (PN) and contribute to the maintenance of pruritus is currently being...…

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