This content is machine translated Modern system therapeutics for hidradenitis suppurativa Immunological dysregulation in the sights of several biologics and “small molecules” The approval of anti-TNF and anti-IL-17 antibody therapies for moderate to severe courses of hidradenitis suppurativa has significantly improved the drug treatment options for this debilitating and potentially mutilating disease...…
View Post 7 min This content is machine translated Atopic dermatitis as a door opener for an atopic cascade? AD trajectories: Summary of current findings Epidemiologic analyses and longitudinal studies show that the majority of infants affected by AD are symptom-free as adults, but in some, AD persists into adulthood. This is associated with an...…
View Post 6 min This content is machine translated Prurigo nodularis: evidence-based treatment Targeted therapy options on the rise The pathophysiology of prurigo nodularis (PN) is multifactorial and complex, but great progress has recently been made in terms of treatment options. In addition to the monoclonal antibodies dupilumab and...…
View Post 5 min This content is machine translated Severe asthma and CRSwNP Multidisciplinary collaboration between pneumology, allergology and ENT Severe eosinophilic asthma (SEA) and chronic rhinosinusitis with nasal polyps (CRSwNP) are overlapping clinical entities united by a common pathophysiological basis of type 2 inflammation. The frequent co-occurrence of these...…
View Post 5 min This content is machine translated Seborrheic dermatitis in adults Do not underestimate the symptom burden Seborrhoeic eczema is caused by a complex interplay of dysbiosis, impaired skin barrier function and immunological dysregulation. It occurs preferentially in areas rich in sebaceous glands and is associated with...…
View Post 5 min This content is machine translated Moderate to severe atopic dermatitis Established and novel biologics – the therapeutic landscape is in flux Clinically, atopic dermatitis (AD) manifests itself through a polymorphic picture of efflorescences, with pruritus and xerosis in the foreground. In addition to the antibody therapies dupilumab, tralokinumab and lebrikizumab, which...…
View Post 4 min This content is machine translated Case series Mast cell activation syndrome (MCAS) MCAS is now understood as an independent disorder in contrast to systemic or cutaneous mastocytosis. The signs and symptoms can affect the skin, the gastrointestinal tract and the cardiovascular system,...…
View Post 9 min This content is machine translated Irritable Bowel Syndrome “Best practice” recommendations for step-by-step clarification and stage-adapted therapy The diagnosis of irritable bowel syndrome (IBS) is based on the Rome IV criteria for functional gastrointestinal disorders. The main symptoms are abdominal pain and altered bowel habits, but patients...…
View Post 10 min This content is machine translated Contact eczema Causes and prevention at work Occupational groups with a high risk of developing occupational eczema include jobs with increased wet work and/or exposure to allergens. Initially, irritant hand eczema typically occurs, which can be a...… CME-Test
View Post 6 min This content is machine translated Hidradenitis suppurativa: biologics reduce inflammatory processes Treatment recommendations depend on the severity and inflammatory activity Due to its phenotypic heterogeneity and multifactorial pathogenesis, hidradenitis suppurativa is a complex disease that can be difficult to treat. Fortunately, research has achieved significant breakthroughs in the recent past,...…
View Post 4 min This content is machine translated Acne treatment: current trends What role do dermocosmetics play? Acne vulgaris is characterized by excessive sebum production, inflammation and impaired skin barrier function. Effective treatments should target both lesion reduction and skin hydration while being well tolerated. In this...…
