This content is machine translated Advanced breast cancer Next-generation SERD therapy with promising results The results of the Phase III EMBER-3 trial of imlunestrant, a next-generation oral selective oestrogen receptor degrader (SERD) for patients with hormone receptor-positive breast cancer in ER-positive, HER2-negative advanced breast...…
View Post 6 min This content is machine translated Urticaria & urticaria-like exanthema Case studies from pediatric dermatology The lifetime prevalence of urticaria is almost 20%. Second-generation antihistamines are also recommended as first-line therapy for pediatric patients. However, pediatric patients with itchy wheals are not always suffering from...…
View Post 6 min This content is machine translated Vitiligo in children and adolescents Just don’t bury your head in the sand! This dermatosis, which is based on the destruction of melanocytes, can occur at any age – however, it usually affects 10-30 year olds and in over a third of cases...…
View Post 4 min This content is machine translated Innovative care concepts: HÄPPI project Future-oriented model for interprofessional primary care New care models are innovative forms of cooperation and service provision in outpatient primary medical care that offer higher quality and are more efficient at the same time. In Baden-Württemberg,...…
View Post 3 min This content is machine translated Hodgkin's lymphoma No more transplants for relapsed or refractory HL in the future? The standard treatment approach for relapsed or refractory (RR) classical Hodgkin’s lymphoma (HL) after failure of first-line treatment is second-line therapy with the aim of achieving complete remission (CR), followed...…
View Post 5 min This content is machine translated Obesity in childhood and adolescence Multifactorial disease with multiple implications The prevalence of obesity in children and adolescents has risen in recent decades. The categorization of BMI is age- and gender-specific. Studies show that BMI status at a young age...…
View Post 3 min This content is machine translated Gram-negative foot infection Not to be taken lightly Infections of wounds in the foot area are common and correct classification is sometimes a challenge. In Gram-negative foot infections, clinical findings form the backbone of the diagnosis. Local therapy...…
View Post 4 min This content is machine translated CHD: Management after revascularization Individualization of antithrombotic therapy Coronary heart disease (CHD) is one of the most common heart diseases worldwide and is currently grouped into two syndromes: acute coronary syndrome (ACS) and chronic coronary syndrome (CCS). Following...…
View Post 4 min This content is machine translated Biologics for atopic dermatitis Th2 cytokines in focus: proven and new targets The range of antibody therapies for atopic dermatitis (AD) has expanded once again in Europe. In addition to dupilumab and tralokinumab, lebrikizumab is another biologic available in this country that...…
View Post 4 min This content is machine translated Oral JAK-i in atopic dermatitis Benefits and risks: What does the current data say? Although there have been no recent approvals of oral JAK inhibitors (JAK-i) for atopic dermatitis (AD), some interesting study findings have been published. These shed light on the safety of...…
View Post 4 min This content is machine translated Prurigo nodularis Retrospective analyses of large data sets from everyday practice Prurigo nodularis (PN) is a chronic inflammatory skin disease that manifests itself as extremely itchy hard nodules. Prof. Dr. med. Dr. rer nat. Enno Schmidt from the University Hospital Schleswig-Holstein...…