This content is machine translated Autoimmune Liver Diseases Innovative Treatment Approaches for PBC, PSC, and AIH: What’s New? PPAR agonists as second-line therapy have proven effective in primary biliary cholangitis (PBC) not only in clinical trials but also in real-world settings, as recent research findings show. In primary...…
View Post 5 min This content is machine translated Psoriasis in the Age of Precision Medicine Systemic Therapy for Patients with Comorbidities: What Is the Best Choice? Psoriasis is a chronic inflammatory systemic disease often associated with comorbidities, a fact that must be taken into account during treatment. Particular attention should be paid to psoriatic arthritis (PsA),...…
View Post 4 min This content is machine translated MASH Pharmacotherapies as “Game Changers”—What Are the Upcoming Challenges? Two drug therapy options—semaglutide (s.c.) and resmetirom (oral)—are now approved in the EU and the U.S. for the treatment of MASH. This is a major breakthrough, especially since, for a...…
View Post 5 min This content is machine translated Older patients with atopic dermatitis Why the Use of Biologics Is Recommended In light of demographic trends, an increase in the prevalence of atopic dermatitis is also being observed among the elderly population. Tailored treatment plans take into account a wide range...…
View Post 3 min This content is machine translated Asthma in Adults: Bronchodilation and Anti-Inflammatory Therapy Remodeling can be counteracted through a proactive treatment strategy If certain key, evidence-based principles are followed, remission is now an achievable goal in asthma treatment. First, it is recommended to routinely supplement spirometry with a blood test to measure...…
View Post 6 min This content is machine translated Secondary prevention after ACS: individually optimized lipid management Trend towards early combination therapy and new strategies for lowering Lp(a) Secondary prevention after an acute coronary syndrome (ACS) is crucial for improving quality of life and reducing morbidity and mortality rates. Elevated blood lipid levels such as LDL cholesterol and...…
View Post 5 min This content is machine translated Suspicion of neuroborreliosis? Detection of borrelia-specific CSF parameters provides certainty A neurological manifestation occurs in 3-15% of Lyme borreliosis infections and can manifest itself, for example, as polyradiculitis, meningitis or, in rare cases, encephalomyelitis. If neuroborreliosis is suspected, it is...…
View Post 7 min This content is machine translated Crohn's disease: focus on long-term results “Top-down” approach or classic step therapy? The standard treatment of Crohn’s disease (Crohn’s disease) is based on the “step-up” strategy. However, results from the PROFILE study indicate that in newly diagnosed Crohn’s disease, early use of...…
View Post 6 min This content is machine translated Pre-acclimatization on Mount Everest Exploring the physiological limits Traditionally, a period of six to nine weeks is planned for an Everest expedition. This established practice was called into question in 2025 when five British mountaineers climbed Everest in...…
View Post 5 min This content is machine translated Sarcoidosis New options from JAKi to mTOR Despite decades of clinical experience, the treatment of sarcoidosis remains a challenge. Although established treatment strategies such as corticosteroids, methotrexate or TNF-alpha blockers are available, the options are limited, particularly...…
View Post 6 min This content is machine translated Head and neck squamous cell carcinoma Precision immunotherapy and local treatment The role of immunotherapy in the treatment of locally advanced head and neck squamous cell carcinoma (LA-HNSCC) is currently being reassessed. At the SOHC Congress 2025 in Basel, Yungan Tao...…
