This content is machine translated Acute nonspecific back pain Implementing a biopsychosocial approach Acute pain in the lower back (low back pain) is a common condition. In primary care, the initial focus is on relieving pain and ruling out “red flags.” A patient-centered...…
View Post 8 min This content is machine translated Alopecia areata Should I recommend topical or systemic treatment? For localized and limited hair loss, first-line treatment usually involves the use of corticosteroids, which are administered in topical formulations and/or as intralesional injections. Topical minoxidil is another treatment option...…
View Post 5 min This content is machine translated Idiopathic pulmonary arterial hypertension (iPAH) Not all precapillary PH is the same Pulmonary arterial hypertension (PAH) is hemodynamically defined by elevated pressure in the pulmonary vascular circulation. It was long considered a “model disease” because it often affected young women with no...…
View Post 7 min This content is machine translated Acne vulgaris: Topical and Systemic Treatment Options Spotlight on “Hot Topics” The recent reapproval of topical clascoterone in the U.S., the EU, and the U.K. represents a significant expansion of the therapeutic arsenal. Regarding benzoyl peroxide (BPO), the debate over whether...…
View Post 6 min This content is machine translated Wrinkle Treatment with Botulinum Toxin: Current Trends The “Hotspots” Theory and the Moose Injection Technique A recent review article summarized findings on motor microinnervation and the topography of neuromuscular end plates in the muscles of the upper half of the face to facilitate the best...…
View Post 8 min This content is machine translated Chronic Urticaria: Treatment for Patients Unresponsive to Antihistamines In addition to anti-IgE antibodies, the guideline recommends anti-IL-4α antibodies and BTK inhibition The 2026 revised edition of the international urticaria guidelines incorporates the latest findings on pathogenesis and treatment options. Chronic spontaneous urticaria (CSU) encompasses various immunological endotypes with implications for the...…
View Post 5 min This content is machine translated Rare Pathogens in CAP When pneumonia is not “typical” Rare pathogens causing community-acquired pneumonia (CAP) represent clinically relevant differential diagnoses—particularly in cases of atypical clinical courses, lack of response to treatment, or unusual imaging findings. Filamentous bacteria such as...…
View Post 5 min This content is machine translated New COPD Treatments Targeting the inflammation—but for whom and when? Up to 50% of people with COPD continue to experience exacerbations despite receiving maximum inhaled therapy. The key factor here is persistent chronic inflammation, which cannot be fully controlled even...…
View Post 4 min This content is machine translated Chronic Hepatitis B: Is a Cure in Sight? Phase III Trial of Temporary Treatment with Bepirovirsen Was Successful Hepatitis B is the most common form of viral hepatitis worldwide—dreaded complications include liver cirrhosis and hepatocellular carcinoma (HCC). Treatment with Bepirovirsen, an antisense oligonucleotide that targets mRNAs of the...…
View Post 5 min This content is machine translated Clinically Suspected Arthralgias “Watchful waiting” or intervention? The pathogenesis of rheumatoid arthritis (RA) begins years before clinical manifestation, but not all patients with joint pain develop RA. Since the primary care physician or internist’s office is usually...…
View Post 6 min This content is machine translated Upper GI Tract Bleeding: Hematemesis, Hematochezia, or Melena? From Risk Stratification to Post-Endoscopic Management Managing patients with acute upper gastrointestinal bleeding can be a balancing act. Clinical scores are helpful for time-sensitive risk assessment in the emergency department: Is the patient stable? Is urgent...…
