This content is machine translated Ulcerative colitis: current evidence on anti-inflammatory therapies Remission induction and maintenance with biologics and JAK-i The most important therapeutic goal in ulcerative colitis is clinical and endoscopic remission. For moderate to severe disease activity, various options for therapy escalation are available. A non-interventional study examined...…
View Post 4 min This content is machine translated Bronchiectasis New strategies against neutrophilic inflammation While bronchiectasis has long been regarded primarily as a consequence of chronic infections, neutrophilic inflammation is increasingly coming into focus as a key driver of progression and exacerbations. This is...…
View Post 7 min This content is machine translated Orthobiologics for knee osteoarthritis PRP and hyaluronic acid injections as building blocks in a multimodal concept Conservative arthrosis therapy aims to alleviate pain and maintain mobility, whereby the measures should be individually tailored to the patient. In addition to addressing lifestyle factors, physiotherapy and physical applications...…
View Post 5 min This content is machine translated Omaveloxolone for Friedreich's Ataxia Efficacy and Safety Studied Over 6 Years Friedreich’s ataxia is associated with multisystemic manifestations such as cardiomyopathy, scoliosis, and diabetes. The progression of the disease is typically characterized by a gradual decline in neurological function and activities...…
View Post 6 min This content is machine translated Psoriasis: therapy with biologics and TYK-2-i Progress assessments based on current long-term and real-world data A broad spectrum of systemic agents is now available for the treatment of moderate to severe psoriasis. At this year’s DDG congress “Dermatology compact + practical”, various studies were presented...…
View Post 4 min This content is machine translated Hypertension: the most important facts for daily practice Early dual antihypertensive therapy is usually indicated 95% of all hypertensive patients have primary hypertension. Over the years, the classification has evolved into a more differentiated system. The current ESC guideline, for example, differentiates between hypertension, raised...…
View Post 3 min This content is machine translated Gastric carcinoma Ways of precision oncology New study data are fundamentally changing first-line treatment of metastatic gastric cancer. The ESMO on Air webinar on March 12, 2025 showed how biomarkers guide therapy selection and open up...…
View Post 8 min This content is machine translated When basal cell carcinomas prove difficult to treat Reaching the goal with innovative therapy strategies The further development of patient-oriented, function-preserving treatment strategies is an important concern of skin cancer research. For patients with advanced cutaneous basal cell carcinoma (BCC), there is a need for...…
View Post 6 min This content is machine translated Type 2 diabetes: sarcopenia and frailty How can the breakdown of skeletal muscles be stopped? Insulin resistance, dyslipidemia, lack of exercise, inflammation and hypertension are among the most common risk factors for sarcopenia. Along with a loss of muscle mass and function, the risk of...…
View Post 4 min This content is machine translated Trichophyton indotineae Terbinafine-resistant dermatophytoses are on the rise in Central Europe Trichophyton indotineae (T. indotineae) often causes persistent, recurrent skin infections and is spreading worldwide. The fact that the number of cases has also increased in Central Europe in recent years...…
View Post 7 min This content is machine translated Disease-modifying therapies for ATTR-CM TTR stabilizers, gene silencing and gene scissors: where do we stand? Advances in the understanding of the pathophysiology of transthyretin amyloid cardiomyopathy (ATTR-CM) have revolutionized the therapeutic landscape in recent years. TTR stabilizers such as tafamidis and acoramidis can reduce TTR...…