This content is machine translated IgA Nephropathy: The Evolving Landscape of Treatment What are the most important game-changers? IgA nephropathy, also known as “Berger’s disease,” is the most common form of glomerulonephritis worldwide. It is an immune-mediated kidney disease diagnosed based on urine test results and a kidney...…
This content is machine translated Chronic Lymphocytic Leukemia (CLL) Personalized Therapy in the Age of Targeted Drugs New data on the use of pirtobrutinib in treatment-naive patients with chronic lymphocytic leukemia were presented at the 2026 ASCO Annual Meeting. The results from the Phase 3 studies BRUIN...…
View Post 3 min This content is machine translated HGSOC PARP-based, molecular, and immunological therapeutic approaches At ASCO 2026, various therapeutic approaches for high-grade serous ovarian cancer (HGSOC) were presented. These included current data on genome-wide HRD characterization in the context of PARP maintenance therapy and...…
View Post 4 min This content is machine translated Hepatitis B: New Analysis of the B-SURE Study Bepirovir without prior nucleoside analog therapy Innovative therapies focus either on reducing viral load or on stimulating HBV-specific immune cells—or both. The B-CLEAR study on bepirovir included two parallel cohorts: HBV patients with and without prior...…
View Post 7 min This content is machine translated Lupus Nephritis – Countering the Attack on the Immune System Innovative adjunctive therapies promote renal remission Early diagnosis and treatment of lupus nephritis can be crucial for preserving kidney function. Among the adjunctive immunomodulatory therapies, two B-cell-targeted antibodies with different mechanisms of action—belimumab and obinutuzumab—are now...…
View Post 4 min This content is machine translated 2026 Vaccination Schedule: Important Changes Updated Recommendations on Pneumococcal Disease and RSV Competent medical counseling can help promote acceptance of vaccinations. To this end, it is crucial to always have the most up-to-date information. The current immunization schedule includes several relevant changes...…
View Post 6 min This content is machine translated COPD: Biomarker-Guided Therapy Escalation Biologics as the “new kids on the block” What led to a paradigm shift in severe asthma several years ago is now also making its way into COPD treatment: targeted, phenotype-specific antibody therapy. Patients with severe COPD who...…
View Post 3 min This content is machine translated Performance Characteristics and Asymmetries in Badminton Differences in Oxygenation Patterns Among Female Badminton Players In competitive badminton, injuries can impair performance and training. Researchers therefore examined muscular asymmetries, local muscle oxygenation, and sport-specific performance parameters in female badminton players of varying skill levels. Differences...…
This content is machine translated Changes in Asthma Treatment From SABA to the biannual biology exam In 2015, the GINA guidelines in effect at that time primarily recommended as-needed treatment with a short-acting β2-agonist (SABA) for mild asthma. Over the past ten years, asthma treatment has...…
View Post 5 min This content is machine translated Advanced Lung Diseases in Older Adults An Integrated Approach to Pulmonology, Geriatrics, and Palliative Care As people age, the prevalence of classic pulmonary diseases such as COPD, pneumonia, or bronchial carcinoma typically increases. However, a pulmonary diagnosis alone does not determine the course of the...…
View Post 6 min This content is machine translated Liver Cancer Artificial Intelligence in Precision Oncology—Opportunities and Challenges The 2025 ESMO Congress covered a wide range of translational and clinical topics, with the growing importance of artificial intelligence (AI) in diagnosis, prognosis, and treatment decisions standing out in...…