This content is machine translated Irritable Bowel Syndrome Functional disorder of gut-brain interaction – a biopsychosocial concept According to recent findings, irritable bowel syndrome is one of the disorders of the gut-brain axis. Stress, intestinal permeability and inflammatory processes play an important role here. In clinical practice,...…
View Post 6 min This content is machine translated Abdominal aortic aneurysms in primary care Risk-stratified screening and prophylaxis As abdominal aortic aneurysms are usually asymptomatic but potentially life-threatening, patients at risk should be screened in a targeted manner. These include in particular men over 65 and patients with...…
View Post 6 min This content is machine translated Hypertrophic cardiomyopathies (HCM) How do myosin inhibitors perform in different HCM phenotypes? Cardiac myosin inhibitors have been developed as a targeted therapeutic option for modulating sarcomere function. While in clinical trials in obstructive hypertrophic cardiomyopathy they brought about a greater improvement in...…
View Post 8 min This content is machine translated When basal cell carcinomas prove difficult to treat Reaching the goal with innovative therapy strategies The further development of patient-oriented, function-preserving treatment strategies is an important concern of skin cancer research. For patients with advanced cutaneous basal cell carcinoma (BCC), there is a need for...…
View Post 10 min This content is machine translated Patients with leg swelling DVT and other common DDs with peripheral edema Swelling of the lower extremities is common, especially in older adults. Due to the complex interrelationships, the clarification of such findings in general practice is a challenge. The differential diagnostic...…
View Post 8 min This content is machine translated Obesity treatment: new study data Incretin mimetics for comorbidities such as type 2 diabetes, ASCVD, HF, OSAS Lifestyle-related measures are the basic framework in the treatment of overweight and obesity. However, in order to achieve and maintain the target weight, accompanying pharmacological or surgical measures are usually...…
View Post 6 min This content is machine translated Type 2 diabetes: sarcopenia and frailty How can the breakdown of skeletal muscles be stopped? Insulin resistance, dyslipidemia, lack of exercise, inflammation and hypertension are among the most common risk factors for sarcopenia. Along with a loss of muscle mass and function, the risk of...…
View Post 6 min This content is machine translated MASLD/MASH: lifestyle, pharmacotherapy, bariatric procedures Addressing metabolic drivers and counteracting fibrosis Steatotic liver diseases that are not associated with alcohol consumption are now referred to as metabolic steatotic liver disease (MASLD) or metabolic dysfunction-associated steatohepatitis (MASH). There is now no need...…
View Post 5 min This content is machine translated Atrial fibrillation Anticoagulation after catheter ablation – for how long? In selected groups of patients with atrial fibrillation, ablation can lead to an improvement in symptoms and/or prognosis. To avoid complications, anticoagulation before, during and after ablation should be criteria-driven....…
View Post 4 min This content is machine translated Wound treatment and dermal defect coverage Fish skin matrix for the treatment of complex ulcers The treatment of complex wounds, particularly large and deep skin defects, is a considerable challenge and there is a need for innovative approaches. As various case reports from clinical practice...…
View Post 6 min This content is machine translated Treatment of infected wounds and wounds at risk of infection Focus on an interdisciplinary perspective Experts from various specialist disciplines questioned common myths about wound care and presented solutions to improve the care situation. One quintessence was that modern wound care requires a paradigm shift...…