This content is machine translated Moderate to severe chronic hand eczema Delgocitinib cream – first topical pan-JAK inhibitor approved in Switzerland In the phase III DELTA 1 and 2 studies, delgocitinib cream showed a rapid onset of efficacy – at week 16, half of the patients achieved a 75% improvement in...…
View Post 4 min This content is machine translated Prurigo nodularis Retrospective analyses of large data sets from everyday practice Prurigo nodularis (PN) is a chronic inflammatory skin disease that manifests itself as extremely itchy hard nodules. Prof. Dr. med. Dr. rer nat. Enno Schmidt from the University Hospital Schleswig-Holstein...…
View Post 4 min This content is machine translated Oral JAK-i in atopic dermatitis Benefits and risks: What does the current data say? Although there have been no recent approvals of oral JAK inhibitors (JAK-i) for atopic dermatitis (AD), some interesting study findings have been published. These shed light on the safety of...…
View Post 4 min This content is machine translated Biologics for atopic dermatitis Th2 cytokines in focus: proven and new targets The range of antibody therapies for atopic dermatitis (AD) has expanded once again in Europe. In addition to dupilumab and tralokinumab, lebrikizumab is another biologic available in this country that...…
View Post 7 min This content is machine translated Study report Scabies treatment: benzyl benzoate in direct comparison with permethrin European guidelines mention permethrin, benzyl benzoate and crotamiton as topical antiscabiosa. There have been repeated reports of treatment failure with permethrin in recent years, although the causes are controversial. In...…
View Post 5 min This content is machine translated Psoriasis Indications of an increased risk of “leaky gut” Psoriasis sufferers often have invisible inflammation in the small intestine along with a tendency to increased permeability of the intestinal barrier (“leaky gut”), according to recently published research from Uppsala...…
View Post 6 min This content is machine translated Case study Pemphigus – from diagnosis to therapy Pemphigus diseases are potentially life-threatening, blistering autoimmune diseases. Acantholysis is detected by skin or mucosal biopsy. In this case study, an 82-year-old man was referred for a dermatological examination due...…
View Post 8 min This content is machine translated Psoriasis treatment with biologics What are the latest trends? Novel oral therapies are currently being researched – promising data from clinical trials is now available. In the field of approved, subcutaneously administered IL-23 and IL-17 antagonists, current real-world data...…
View Post 6 min This content is machine translated Urticaria & urticaria-like exanthema Case studies from pediatric dermatology The lifetime prevalence of urticaria is almost 20%. Second-generation antihistamines are also recommended as first-line therapy for pediatric patients. However, pediatric patients with itchy wheals are not always suffering from...…
View Post 6 min This content is machine translated Vitiligo in children and adolescents Just don’t bury your head in the sand! This dermatosis, which is based on the destruction of melanocytes, can occur at any age – however, it usually affects 10-30 year olds and in over a third of cases...…
View Post 3 min This content is machine translated Gram-negative foot infection Not to be taken lightly Infections of wounds in the foot area are common and correct classification is sometimes a challenge. In Gram-negative foot infections, clinical findings form the backbone of the diagnosis. Local therapy...…
