This content is machine translated Contact eczema Causes and prevention at work Occupational groups with a high risk of developing occupational eczema include jobs with increased wet work and/or exposure to allergens. Initially, irritant hand eczema typically occurs, which can be a...… CME-Test
View Post 8 min This content is machine translated Mastocytosis Innovative pathogenesis-based therapeutic approaches in the pipeline The treatment of mastocytosis has undergone a paradigm shift in recent years. A deeper molecular understanding of the disease has paved the way from a purely symptomatic to a targeted,...…
View Post 7 min This content is machine translated Prurigo nodularis and AD Effective itch relief through inhibition of the IL-31 signaling pathway The vicious circle of itching and scratching is a central element in both prurigo nodularis (PN) and atopic dermatitis (AD). Interleukin (IL)-31, often referred to as the “itch cytokine”, has...…
View Post 4 min This content is machine translated Cutaneous Crohn's disease Effective alternative to TNF inhibitors Cutaneous Crohn’s disease (CCD) is a granulomatous skin disease that is not associated with the gastrointestinal tract. It rarely correlates with intestinal disease and often requires separate treatment. Although interleukin...…
View Post 5 min This content is machine translated Case Report 53-year-old female patient with palmoplantar keratoderma Palmoplantar keratoderma is characterized by excessive epidermal thickening of the skin on the palms and/or plantar surfaces of the feet and can be hereditary or acquired. The spectrum of possible...…
View Post 8 min This content is machine translated GPP: from molecular principles to targeted therapy Therapeutic rationale for targeted IL-36 receptor inhibition The progress in the diagnosis and treatment of generalized pustular psoriasis (GPP) is remarkable. GPP has developed into a clearly defined, independent, IL-36-mediated autoinflammatory disease. Today, the high chronic disease...…
View Post 4 min This content is machine translated Chronic hand eczema Topical pan-JAK-i vs. systemic retinoid: head-to-head study Alitretinoin is currently the only systemic treatment approved for severe chronic hand eczema when patients do not respond adequately to topical corticosteroids. The topical pan-Janus kinase (JAK) inhibitor delgocitinib is...…
View Post 6 min This content is machine translated Actinic keratosis Field-directed therapy methods: what the European guideline recommends Topically applied medications are a cornerstone of the field-directed treatment of actinic keratoses. In photodynamic therapy, a topical agent is combined with a procedural method. In cases of insufficient response,...…
View Post 6 min This content is machine translated Itching in primary biliary cholangitis When the skin becomes agony The agonizing itching is one of the most difficult symptoms to bear in patients with primary biliary cholangitis (PBC). It can have a far greater impact on everyday life, sleep...…
View Post 2 min This content is machine translated TREATswitzerland Register Evaluation of system therapies for AD In addition to conventional immunosuppressants, several monoclonal antibodies (biologics) and Janus kinase inhibitors (JAK-i) are now approved for the systemic treatment of atopic dermatitis (AD) in Switzerland. The primary objective...…
View Post 10 min This content is machine translated Collagenoses Scleroderma – Current recommendations for diagnosis and therapy 2025 Early detection is critical for treatment options of this multisystem disease with cutaneous involvement. Raynaud’s attacks are often in early stages and should always be further evaluated. Advances in research...… CME-Test
