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Dermatology and venereology

1011 posts
  • This content is machine translated Compression

Lymphoedema and chronic wounds

Lymphoedema is a chronic inflammatory disease of the interstitium as a result of primary (congenital) or secondary (acquired) damage to the lymphatic drainage system, which is characterized by inflammation, increased…
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  • 10 min
  • This content is machine translated Podiatry support to improve quality of life

Patient mobility with a foot wound

Podiatrists are therapists who are specially trained in foot and leg therapy and whose area of responsibility extends from preventive, therapeutic and rehabilitative treatment to the fields of dermatology, diabetology,…
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  • 18 min
  • This content is machine translated Hidradenitis suppurativa/acne inversa

Challenges of outpatient care

The disease hidradenitis suppurativa/acne inversa was first mentioned in 1839 with superficial abscesses on the axillary, submammary and perianal regions. To date, the disease has had various names: Perifolliculitis capitis…
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  • 4 min
  • This content is machine translated SLE: Early use of biologics?

Findings from the “Leeds SLE Inception Cohort”

If systemic lupus erythematosus (SLE) cannot be adequately controlled with hydroxychloroquine and cortisone preparations, the use of immunomodulatory or immunosuppressive agents and/or biologics should be considered according to current EULAR…
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  • 4 min
  • This content is machine translated Dermatomyositis

Impaired mitochondrial function as a trigger for SI joint upregulation?

The autoimmune disease dermatomyositis is one of the collagenoses andis characterized by muscular symptoms and characteristic skin florescences. There are indications that the disease is controlled by type I interferon.…
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  • 7 min
  • This content is machine translated Interview with Prof. Thomas Kündig (USZ) and Prof. Diego Kyburz (USB)

“You have to stop treating psoriasis as just a skin disease”.

In Switzerland, psoriasis affects about 1 to 3 percent of the population [1]. About one in three psoriasis patients also suffers from psoriatic arthritis (PsA), a chronic inflammatory systemic disease that…
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  • 4 min
  • This content is machine translated "Small Molecules" at AD

Current analyses of the pioneer among the JAK-i

The first representative of the Janus kinase (JAK) inhibitor class to be approved for atopic dermatitis was baricitinib. In an extensive study program, this selective and reversible inhibitor of JAK-1…
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  • 6 min
  • This content is machine translated Atopic dermatitis and the skin microbiome

How does systemic therapy influence dysbiosis?

One aim of the multicenter observational study ProRaD is to gain a better understanding of the mechanisms that influence the course of atopic dermatitis (AD). In a sub-project, researchers used…
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  • 7 min
  • This content is machine translated Biologics for AD

Interleukin-13 as a target – new long-term data available

Now that the range of systemic therapeutics for atopic dermatitis has been expanded and the two monoclonal antibodies dupilumab and tralokinumab as well as three Janus kinase inhibitors have been…
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  • 6 min
  • This content is machine translated Eosinophilic esophagitis (EoE)

Th2 inflammation plays a central role

EoE is now considered a type 2-mediated immune disease that is often associated with atopic diseases such as atopic dermatitis, asthma and food allergies. In addition to acid blockers (PPI)…
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  • 4 min
  • This content is machine translated TYK2 inhibition in psoriasis

What’s new?

The JAK-STAT pathway mediates a variety of proinflammatory responses through Janus kinases (JAK)1-3 andtyrosine kinase-2 (TYK2).Deucravacitinib selectively inhibits TYK2 and was shown to be effective and safe in patients with…

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