This content is machine translated Moderate to severe chronic hand eczema Delgocitinib cream – first topical pan-JAK inhibitor approved in Switzerland In the phase III DELTA 1 and 2 studies, delgocitinib cream showed a rapid onset of efficacy – at week 16, half of the patients achieved a 75% improvement in...…
View Post 9 min This content is machine translated Wild-type transthyretin amyloid cardiomyopathy (ATTRwt-CA) Diagnosis at an early stage, prognostic classifications and outlook Cardiac amyloidosis, especially wild-type transthyretin amyloid cardiomyopathy (ATTRwt-CA), has become increasingly important in recent years. Originally, it was considered a rare disease with a (mostly) late age of manifestation. Recent...…
View Post 4 min This content is machine translated Case report: Drug-induced hepatitis Rare side effect of tirzepatide therapy The dual glucose-dependent insulinotropic polypeptide (GIP)/glucagon-like peptide 1 (GLP1) receptor agonist triazepatide has shown promise for improving glycemic control and weight loss. However, it can also have undesirable side effects....…
View Post 4 min This content is machine translated Plea for sex-specific neurology Migraine in men: underdiagnosed, underestimated, under-researched Migraine is a highly prevalent primary headache disorder whose gender-specific differences have so far mainly been considered with regard to women. However, migraine in men has special characteristics – both...…
View Post 9 min This content is machine translated Oxidative stress and neurodegeneration Insights and therapeutic strategies for Parkinson’s disease Parkinson’s disease (PD) is a neurodegenerative disease characterized by a progressive loss of dopaminergic neurons in the substantia nigra pars compacta. Oxidative stress is increasingly being discussed as a key...…
View Post 3 min This content is machine translated Teens, Screen and Mental Health How social media influences depression in young people In recent years, social media has become an integral part of young people’s everyday lives. Platforms such as Instagram, TikTok and Snapchat not only determine social interaction, but also self-perception...…
View Post 9 min This content is machine translated Venous thromboembolism prevention PCSK9 inhibitors: Current evidence, mechanisms and unanswered questions Venous thromboembolism (VTE), consisting of deep vein thrombosis (DVT) and pulmonary embolism (PE), is the third most common cause of cardiovascular mortality worldwide after myocardial infarction and stroke. Despite continuous...…
View Post 7 min This content is machine translated Study report Scabies treatment: benzyl benzoate in direct comparison with permethrin European guidelines mention permethrin, benzyl benzoate and crotamiton as topical antiscabiosa. There have been repeated reports of treatment failure with permethrin in recent years, although the causes are controversial. In...…
View Post 14 min This content is machine translated Innovative approaches in glioblastoma treatment Synergistic combination therapies and the potential of phytotherapy and mycotherapy Glioblastomas (GBM) are among the most aggressive and therapy-resistant tumors of the central nervous system and present both clinicians and researchers with immense challenges. Despite significant advances in diagnostics and...…
View Post 5 min This content is machine translated COPD The mountain is calling The development of alpine tourism and the increasing trend towards adventure travel have made high mountain regions accessible not only to healthy people, but also to patients with cardiorespiratory diseases...…
View Post 4 min This content is machine translated Work-related asthma When the job leads to exacerbations Asthma attacks caused by occupational exposure are very common in adults with asthma. Although previous studies have mainly focused on occupational asthma (OA), interest in work-exacerbated ast hma (WEA) has...…