Differentiate chronic inflammatory demyelinating polyneuropathy (CIDP)

CIDP can only be reliably differentiated from clinical mimics through systematic diagnostics. Diagnostic findings guide the selection of suitable immunotherapy. Chronic inflammatory demyelinating polyneuropathy shows diverse phenotypes and is often misdiagnosed. This article summarizes the guideline-compliant diagnostic procedure, explains the role of electrophysiology and shows how variants and antibody profiles determine the choice of immunotherapy.