This content is machine translated Severe asthma Anti-IL-5/-5Rα biologics impress in the real world Three biologics targeting interleukin 5 (IL-5) or its receptor (IL-5Rα) are approved for use in patients with severe asthma. In a meta-analysis, Greek scientists have now investigated the clinical response...…
View Post 10 min This content is machine translated Significance, diagnostics and treatment options for cardiology practice Coronary artery spasm and atherosclerosis Angina pectoris is traditionally regarded as the leading symptom of coronary sclerosis. Nevertheless, observations show that a relevant proportion of patients with typical angina symptoms have no hemodynamically significant stenoses...…
View Post 6 min This content is machine translated Chronic hand eczema Changing therapy landscape – a lot is happening Inflamed, itchy and sometimes painful skin lesions on the hands can significantly impair quality of life. If chronic hand eczema proves to be refractory to topical treatment, systemic therapy is...…
View Post 4 min This content is machine translated Chronic obstructive pulmonary disease Polygenic risk score can help identify COPD Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death in patients worldwide and yet often goes undiagnosed. Although genetic risk plays a significant role in susceptibility...…
View Post 5 min This content is machine translated Bronchiectasis and Pseudomonas aeruginosa infection Statistically significant reduction in the frequency of exacerbations A chronic lung infection with Pseudomonas aeruginosa is associated with an increased exacerbation and mortality rate in people affected by bronchiectasis. Inhaled antibiotics are frequently used in clinical practice to...…
View Post 5 min This content is machine translated Case Report A rare and well-hidden subcutaneous lymphoma Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is rare and has developed into a distinct entity over the last three decades. Traditionally characterized by skin lesions, in this case it presents as...…
View Post 9 min This content is machine translated Psoriasis in locations that are difficult to treat New study data on IL-23 inhibition When psoriasis manifests in palmoplantar and intertriginous regions or on the nails, this often poses a therapeutic challenge. Several recently presented analyses on the effects of anti-IL-23p19 antibodies currently approved...…
View Post 4 min This content is machine translated From symptom to diagnosis Abdominal pain – liver metastases Contrast-enhanced imaging examinations have a high sensitivity and specificity for the detection of liver metastases, whereby sonographic as well as computer and magnetic resonance imaging examinations can be used. The...…
View Post 9 min This content is machine translated Rare diseases: Marfan syndrome Hereditary connective tissue disease with a vascular component Even though targeted genetic tests are now available, the diagnosis of Marfan syndrome is still mainly based on specific clinical criteria, in particular the revised Ghent classification. The broad phenotypic...…
View Post 4 min This content is machine translated New prognostic indicator for idiopathic pulmonary fibrosis Low BAR allows IPF patients to live longer Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fatal and age-related interstitial lung disease whose etiology and pathogenesis are still largely unknown. It is important to identify IPF patients at...…
View Post 4 min This content is machine translated Basic therapy for atopic dermatitis “Emollients plus” with bacterial lysates There are various indications in the specialist literature that the gram-negative, non-pathogenic bacterium Vitreoscilla filiformis (V. filiformis) has a beneficial effect on atopic skin. New findings confirm earlier reports of...…
