This content is machine translated Multiple sclerosis Update on new antigen-specific therapeutic approaches A promising approach for the therapy of multiple sclerosis lies in antigen-specific treatment. They are intended to specifically inhibit the autoreactive immune response to avoid the risks of global immunosuppression.
View Post 2 min This content is machine translated CAR-T cells Focus on innovative cancer therapy CAR-T cells are currently one of the most exciting developments in immunotherapy. It combines immunotherapy, cell therapy and gene therapy and could become a routine treatment in the future.
View Post 10 min This content is machine translated Myeloproliferative neoplasms Polycythemia vera: pathogenesis, clinical, diagnostic and therapeutic implications. Hematopoietic stem cell myeloproliferative neoplasia is predominantly caused by somatic mutations of the JAK2 gene and resulting clonal autonomous hematopoiesis. The risk of myelofibrosis or leukemic transformation are prognostic.
View Post 10 min This content is machine translated Update Cardiogenetics Current advances and limitations in cardiovascular genetics. Genetic testing now enables diagnoses that could not be made in the past. However, it depends on the method, which significance is behind the results.
View Post 6 min This content is machine translated Anxiety disorders What is the role of epigenetics? “We are not our genes!” With this statement, Prof. Katharina Domschke from Freiburg referred to the importance of environmental influences – and how they shape our mental health through epigenetic…
View Post 12 min This content is machine translated Genodermatoses News about Epidermolysis Bullosa The therapeutic focus remains on symptomatic treatment options and the avoidance of provoking factors. Molecular, potentially curative therapeutic options for epidermolysis bullosa are still in the research stage. In the…
View Post 5 min This content is machine translated Terrorist attacks Will the horror live on in future generations? Several studies show that vulnerability to symptoms of post-traumatic stress disorder (PTSD/PTSD) is increased in descendants of trauma survivors. Psychobiological mechanisms involve the hypothalamic-pituitary-adrenocortical axis, among others. The current article…
View Post 2 min This content is machine translated Nanorobots The drugs of the future can be “programmed Autonomous mini-robots made of DNA can be specifically “programmed” to inflict damage on the tumor. The concept has now been proven in the mouse model.
View Post 6 min This content is machine translated Adjuvant chemotherapy in breast carcinoma Multitests for individual indication The use of the four multigene tests MammaPrint, Oncotype DX, EndoPredict and Prosigna may be useful in deciding on adjuvant chemotherapy. In which patients in particular should they be used?
View Post 3 min This content is machine translated Ehlers-Danlos syndrome When the connective tissue does not hold Ehlers-Danlos syndrome (EDS) is a group of congenital disorders of collagen synthesis. It occurs in about 1:5000 to 1:10,000 people and is about equally common in both sexes. There are…
View Post 10 min This content is machine translated Hypertrophic cardiomyopathy (HCM) Genetics and risk stratification for sudden cardiac death. Hypertrophic cardiomyopathy (HCM) is the most common hereditary heart muscle disease. The clinical picture ranges from asymptomatic patients to manifest heart failure and sudden cardiac death (SCD). The mainstay of…
