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Genetics

121 posts
  • This content is machine translated Immunotherapy

Wider use for CAR-T cell treatment possible in the future?

CAR-T cells have solved a central problem in cancer therapy – they make tumors visible again to the immune system. The initial successes in B-cell lymphomas are now attracting a…
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  • 6 min
  • This content is machine translated Scar prevention

Methods ranging from stem cells and autologous cell spray to laser and radiotherapy

Prophylaxis of scars represents an important component of successful wound management. Nowadays, a wide range of invasive and non-invasive measures is available. At the EADV Annual Congress, international experts gave…
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  • 10 min
  • This content is machine translated Multiple sclerosis

Update on new antigen-specific therapeutic approaches

A promising approach for the therapy of multiple sclerosis lies in antigen-specific treatment. They are intended to specifically inhibit the autoreactive immune response to avoid the risks of global immunosuppression.
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  • 2 min
  • This content is machine translated CAR-T cells

Focus on innovative cancer therapy

CAR-T cells are currently one of the most exciting developments in immunotherapy. It combines immunotherapy, cell therapy and gene therapy and could become a routine treatment in the future.
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  • 10 min
  • This content is machine translated Myeloproliferative neoplasms

Polycythemia vera: pathogenesis, clinical, diagnostic and therapeutic implications.

Hematopoietic stem cell myeloproliferative neoplasia is predominantly caused by somatic mutations of the JAK2 gene and resulting clonal autonomous hematopoiesis. The risk of myelofibrosis or leukemic transformation are prognostic.
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  • 10 min
  • This content is machine translated Update Cardiogenetics

Current advances and limitations in cardiovascular genetics.

Genetic testing now enables diagnoses that could not be made in the past. However, it depends on the method, which significance is behind the results.
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  • 6 min
  • This content is machine translated Anxiety disorders

What is the role of epigenetics?

“We are not our genes!” With this statement, Prof. Katharina Domschke from Freiburg referred to the importance of environmental influences – and how they shape our mental health through epigenetic…
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  • 12 min
  • This content is machine translated Genodermatoses

News about Epidermolysis Bullosa

The therapeutic focus remains on symptomatic treatment options and the avoidance of provoking factors. Molecular, potentially curative therapeutic options for epidermolysis bullosa are still in the research stage. In the…
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  • 5 min
  • This content is machine translated Terrorist attacks

Will the horror live on in future generations?

Several studies show that vulnerability to symptoms of post-traumatic stress disorder (PTSD/PTSD) is increased in descendants of trauma survivors. Psychobiological mechanisms involve the hypothalamic-pituitary-adrenocortical axis, among others. The current article…
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  • 2 min
  • This content is machine translated Nanorobots

The drugs of the future can be “programmed

Autonomous mini-robots made of DNA can be specifically “programmed” to inflict damage on the tumor. The concept has now been proven in the mouse model.
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  • 6 min
  • This content is machine translated Adjuvant chemotherapy in breast carcinoma

Multitests for individual indication

The use of the four multigene tests MammaPrint, Oncotype DX, EndoPredict and Prosigna may be useful in deciding on adjuvant chemotherapy. In which patients in particular should they be used?

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