This content is machine translated Multiple myeloma DREAMM-7: Belamaf plus bortezomib and dexamethasone outperforms comparator therapy In patients with multiple myeloma, the disease is often refractory to first-line triple or quadruple therapies. The result: a relapse occurs. Therefore, effective second-line therapy combinations are needed that include...…
View Post 2 min This content is machine translated Acute myeloid leukemia The influence of time from diagnosis to treatment on overall survival Acute myeloid leukemia (AML) is often classified as an oncologic emergency leading to rapid evaluation and treatment in the hospital. Previous studies reported that time from diagnosis to treatment (TDT)...…
View Post 2 min This content is machine translated Acute lymphoblastic leukemia Addition of blinatumomab to chemotherapy improves survival in children Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Children with newly diagnosed B-cell acute lymphoblastic leukemia (B-ALL) with standard risk (SR) have a high survival rate when treated...…
View Post 3 min This content is machine translated Hodgkin's lymphoma No more transplants for relapsed or refractory HL in the future? The standard treatment approach for relapsed or refractory (RR) classical Hodgkin’s lymphoma (HL) after failure of first-line treatment is second-line therapy with the aim of achieving complete remission (CR), followed...…
View Post 2 min This content is machine translated Smoldering multiple myeloma Daratumumab delays progression in smoldering multiple myeloma Smoldering multiple myeloma (SMM) is an asymptomatic premalignant precursor of active multiple myeloma (MM). Results of the presented phase III AQUILA study show that daratumumab significantly delays the progression of...…
View Post 5 min This content is machine translated Case Report A rare and well-hidden subcutaneous lymphoma Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is rare and has developed into a distinct entity over the last three decades. Traditionally characterized by skin lesions, in this case it presents as...…
View Post 3 min This content is machine translated Acute myeloid leukemia QuANTUM wild-type Phase 3 trial for patients with FLT3-ITD-negative AML started Acute myeloid leukemia (AML) is one of the most common forms of leukemia in adults. To date, there are no approved FLT3 inhibitors for patients with FLT3-ITD-negative AML, although sustained...…
View Post 12 min This content is machine translated Diabetic ketoacidosis Recommendations for action in practice Diabetic ketoacidosis (DKA) is an acutely life-threatening complication of diabetes mellitus that occurs predominantly in type 1 diabetes, but is also increasingly occurring in people with type 2 diabetes. A… CME-Test
View Post 5 min This content is machine translated LDL cholesterol level On the way to the (LDL-C) target Cardiovascular disease ( CVD) is the leading cause of death worldwide. Lowering the level of LDL cholesterol (LDL-C) in the blood reduces the risk of CVD such as heart attacks…
View Post 4 min This content is machine translated Diffuse large B-cell lymphoma T-cell-based therapy “off the shelf” Two types of T-cell-based therapy are available for refractory or relapsing diffuse large B-cell lymphoma (DLBCL): CAR T cells and bispecific antibodies. While CAR T cells have revolutionized individualized medicine…
View Post 4 min This content is machine translated Aplastic anemia Etiology and severity as criteria for therapy selection Aplastic anemia is associated with bone marrow hypocellularity and pancytopenia. In patients with immune-mediated severe or very severe aplastic anemia for whom bone marrow transplantation is not an option, the…
