This content is machine translated Pulmonary sarcoidosis Prednisone vs. MTX: a draw after 24 weeks Pulmonary sarcoidosis remains a persistent clinical challenge in respiratory medicine. Although glucocorticoids have long been the mainstay of first-line therapy, their side effects often complicate long-term treatment. In recent years,...…
View Post 4 min This content is machine translated Multiple sclerosis Vitamin D as an adjuvant in multiple sclerosis: statistical success and clinical limitations Various risk factors are involved in the pathogenesis of multiple sclerosis, with vitamin D deficiency being associated with an increased risk of MS since the 1970s. Disease-modifying therapies aim to...…
View Post 5 min This content is machine translated Side effects under opioid therapy Is it possible to avoid the inevitable? Opioid analgesics are an essential tool for the relief of cancer-related pain. However, in addition to their undeniable therapeutic value, opioids are associated with a number of predictable side effects...…
View Post 6 min This content is machine translated Chronic insomnia in adults: Guideline recommendations CBT-i as first choice – pharmacotherapy as secondary intervention Sleep disorders are often associated with pronounced daytime sleepiness, difficulty concentrating and increased feelings of stress. Diagnosis is generally based on the clinical history; if necessary, an actigraphy or polysomnigraphy...…
View Post 4 min Education Geriatrics Neurology Pharmacology and toxicology RX Studies Opicapon: double benefit for motor function and sleep in Parkinson’s disease Sleep disorders are among the most common non-motor Parkinson’s symptoms. The targeted treatment of sleep disorders is an important part of Parkinson’s therapy and can significantly improve quality of life....…
View Post 9 min This content is machine translated Parkinson's disease: progressive and clinically heterogeneous Individualized management of motor and non-motor symptoms Primary care providers are the central point of contact for the early detection of Parkinson’s disease, but collaboration with neurological specialists is essential. The diagnosis is still primarily made clinically....…
View Post 5 min This content is machine translated Multiple sclerosis Avoiding the nocebo trap with natalizumab biosimilars Monoclonal antibodies such as natalizumab are indispensable for multiple sclerosis therapy. A first recently approved biosimilar is clinically equivalent, as studies have shown. Nevertheless, reservations are widespread in practice. Patients...…
View Post 5 min This content is machine translated Antithymocyte globulin in children with T1D Old medicine, new hope The well-known immunomodulatory drug antithymocyte globulin (ATG) can effectively inhibit the progression of type 1 diabetes (T1D) in young patients at low doses, while at the same time having a...…
View Post 3 min This content is machine translated Development of a quintuple agonist New strategy in the fight against obesity and T2D The treatment of obesity and type 2 diabetes is increasingly shifting to newer incretin drugs, including GLP1 receptor agonists (single agonists such as semaglutide) and GIP- and GLP1-RA (dual agonists...…
View Post 6 min This content is machine translated Obesity in the family practice Aim for realistic goals and avoid apportioning blame Morbid obesity is a significant health risk factor and its prevalence has increased in many industrialized countries in recent years. The principles of weight reduction have hardly changed over the...…
View Post 9 min This content is machine translated Psoriasis: intervening in the inflammatory cascade Advantages of early biologic therapy and oral peptide as a beacon of hope The question of whether early biologics treatment can have a lasting effect on the course of psoriasis is the focus of numerous research projects. The GUIDE study investigated the corresponding...…
