This content is machine translated Glomerulonephritis: IgA nephropathy Pathogenesis-based and nephroprotective therapeutic approaches Immunoglobulin (Ig) A nephropathy is considered an important cause of end-stage renal failure. Therefore, from today’s perspective, IgA nephropathy should not be classified as a benign disease. Fortunately, the treatment...…
View Post 6 min This content is machine translated Postmenopausal osteoporosis: long-term therapy concepts Targeted use of antiresorptives and osteoanabolic agents and avoid “rebound” effects Postmenopausal osteoporosis in women is a consequence of decreasing oestrogen levels and is associated with rapid bone loss (“high-turnover osteoporosis”). Long-term therapy concepts are required to achieve sustainable effects –...…
View Post 6 min This content is machine translated Late-onset rheumatoid arthritis More DMARDs can reduce glucocorticoids in LORA Although glucocorticoids have no influence on the course of the disease, they are effective agents against symptomatic pain and inflammation in rheumatoid arthritis (RA). Patients with late onset RA (LORA)...…
View Post 16 min This content is machine translated Pain and autism Hurdles to pain treatment for autistic patients In contrast to neurotypical patients, the brains of neurodivergent people develop differently from the norm. Autism is defined as a form of neurodivergence. For them, deviant stimulus processing is the...… CME-Test
View Post 3 min This content is machine translated Bronchodilators for asthma The early bird … gasps for air Current findings indicate that the biological clock plays an important role in the pathogenesis of bronchial asthma. However, the influence of circadian and seasonal rhythms on the response to bronchodilators...…
View Post 6 min This content is machine translated Chronic musculoskeletal pain How can the use of analgesics be optimized in multimodal therapy? Musculoskeletal pain is complex and often underestimated. Pain sensitization plays an important role in chronification. In the long-term use of currently available analgesics, there may be conflicting goals with regard...…
View Post 6 min This content is machine translated New evidence on genetics, pathophysiology and clinical significance Migraine with and without aura – two different entities? Migraine is one of the most common neurological disorders, and for decades it has been debated whether migraine with aura (MwA) and migraine without aura (MwoA) are merely different manifestations...…
View Post 6 min This content is machine translated Treatment of vitiligo Focus on patient perspective and disease activity In vitiligo, hypopigmented or depigmented areas of skin occur as a result of an autoimmune disorder. The results of a large international survey confirm that vitiligo sufferers sometimes experience considerable...…
View Post 2 min This content is machine translated Chronic pain Nano-ECS modulator Adezunap improves therapy success Cannabinoids have established themselves as therapeutic options in the treatment of pain in recent years. Nevertheless, patients can experience problems when using them, particularly with regard to tolerance. A new...…
View Post 4 min This content is machine translated Gastrointestinal complaints PPI regulation under the microscope Proton pump inhibitors (PPIs) are very effective and suitable for certain indications and treatment periods, but there is an increasing trend towards “off-label” prescriptions. To ensure that temporary administration for...…
View Post 6 min This content is machine translated Pediatric multiple sclerosis Early high efficacy as the key to improving prognosis Pediatric multiple sclerosis (POMS) is a rare but particularly challenging form of the disease. Children and adolescents with MS often experience more relapses, a greater lesion burden on MRI and...…