This content is machine translated The Brain and the Motivation to Eat Why is it so hard to lose weight? Obesity is the most common chronic disease in Western societies, with serious metabolic, cardiovascular, and psychosocial consequences. The therapeutic landscape has changed fundamentally: new-generation GLP-1 agonists achieve weight loss that,...… CME-Test
View Post 12 min This content is machine translated Global Recommendation, Swissmedic Approval, and SL Limitation WHO Guidelines on GLP-1 for Obesity With the guideline published on December 1, 2025, the World Health Organization has, for the first time, issued a globally applicable recommendation on the pharmacological management of obesity in adults....…
View Post 3 min This content is machine translated Tinea capitis: Current Guidelines and Recommendations What should be kept in mind when treating adult patients? Tinea capitis is less common in adults, but its incidence is on the rise. From a diagnostic perspective, one should be on the lookout for pathogens that are rather atypical...…
View Post 12 min This content is machine translated SURPASS-CVOT Tirzepatide versus Dulaglutide in T2D with ASCVD GLP-1 receptor agonists have established themselves in recent years as a class of drugs with cardiovascular protective effects in type 2 diabetes. For dulaglutide, the 2019 REWIND study showed that...…
View Post 5 min This content is machine translated Viloxazine for ADHD A non-stimulating option—but with limited evidence ADHD affects about 5–7% of children and adolescents and 2–5% of adults. Although it is generally considered a childhood disorder, symptoms persist into adulthood for the majority of those affected....…
View Post 6 min This content is machine translated Schizophrenia in the early-onset stage Which antipsychotic should be used for treatment-naive patients? Schizophrenia often develops during adolescence or early adulthood. Neurocognitive deficits frequently occur before or during the first psychotic episode and are closely associated with poorer functional outcomes. However, the effects...…
View Post 6 min This content is machine translated Psoriasis: therapy with biologics and TYK-2-i Progress assessments based on current long-term and real-world data A broad spectrum of systemic agents is now available for the treatment of moderate to severe psoriasis. At this year’s DDG congress “Dermatology compact + practical”, various studies were presented...…
View Post 4 min This content is machine translated Escitalopram for anxiety disorders Positive effect, but no immediate improvement in symptoms Anxiety disorders are among the most common psychiatric illnesses worldwide. There is evidence that both the amygdala and the dorsomedial cortex are involved in the pathophysiology. Selective serotonin reuptake inhibitors...…
View Post 4 min This content is machine translated Ozanimod for relapsing-remitting multiple sclerosis Signs of improved tolerability with prolonged treatment Ozanimod, a selective modulator of sphingosine-1-phosphate (S1P) receptors 1 and 5, has demonstrated efficacy in relapsing-remitting multiple sclerosis (RMS) in Phase 2 and 3 studies. At a dose of 0.92...…
View Post 5 min This content is machine translated Gepante for Migraines Relief from pain, symptoms, and improved functional ability—both acute and preventive Migraine management goes beyond acute symptom control and may also include preventive strategies for patients with a significant disease burden. Although triptans remain the recommended first-line treatment for acute migraine,...…
View Post 3 min This content is machine translated Psoriasis Research: What's in the Pipeline? Highly selective oral TYK inhibitors in Phase III Envudeucitinib and Zasocitinib are oral, allosteric tyrosine kinase 2 (TYK2) inhibitors currently being evaluated in clinical trials for plaque psoriasis. The interim results presented during the Late-Breaking Research sessions at...…
