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Pharmacology and toxicology

301 posts
  • This content is machine translated Side effects under opioid therapy

Is it possible to avoid the inevitable?

Opioid analgesics are an essential tool for the relief of cancer-related pain. However, in addition to their undeniable therapeutic value, opioids are associated with a number of predictable side effects...…
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  • 4 min
  • This content is machine translated Phobia

Propranolol and spider phobia: the time window is crucial

A new study on spider phobia shows that propranolol only works in the long term if those affected re-encounter the fear-inducing stimulus early on. This brings reconsolidation into sharper focus...…
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  • 8 min
  • This content is machine translated Pharmacological therapy

Anxiety symptoms in eating disorders

Eating disorders are mental illnesses that are strongly influenced by biological, psychological and social stress factors. Anxiety symptoms are among the most common and most impairing accompanying symptoms. The systematic...…
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  • 5 min
  • This content is machine translated Evidence-based diagnostics and treatment in the medical setting

Anxiety and depression disorders in adolescence

The prevalence of clinically relevant anxiety and depression symptoms in children and adolescents has increased significantly in recent years. While around 7% of adolescents worldwide reported elevated anxiety symptoms and...…
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  • 4 min
  • This content is machine translated Acne treatment: current trends

What role do dermocosmetics play?

Acne vulgaris is characterized by excessive sebum production, inflammation and impaired skin barrier function. Effective treatments should target both lesion reduction and skin hydration while being well tolerated. In this...…
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  • 4 min
  • This content is machine translated Psoriasis and metabolic comorbidities: new study data

GLP-1RAs showed a valuable dual benefit

GLP-1RAs, including semaglutide and liraglutide, are frequently used today for the treatment of type 2 diabetes and obesity. A recent study investigated whether and how overweight and/or diabetic psoriasis patients...…
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  • 5 min
  • This content is machine translated Consequences for pathophysiology, clinic and therapy

The inflammatory subgroup of major depression

Major depression remains one of the leading causes of disability and suicidality worldwide. A key reason for the inadequate effectiveness of many treatments is their marked biological and clinical heterogeneity....…
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  • 3 min
  • This content is machine translated Sleep disorder

Sleep medicine in transition: new goals and a reassessment of old hypnotics

Sleep and circadian rhythm disorders (SCRDs) often occur as early comorbidities in neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), often decades before typical symptoms appear. Sleep...…
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  • 5 min
  • This content is machine translated Osteoporosis

Risk-stratified therapy with osteoanabolic agents improves outcomes

Patients with a very high or imminent fracture risk should be considered for (first-line) therapy with ostoanabolic substances. Both patient selection and planning of therapy sequences are decisive factors for...…
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  • 4 min
  • This content is machine translated Epilepsy

Cannabidiol for refractory epilepsy syndromes

The pharmaceutical formulation of high-purity cannabidiol is approved for the treatment of seizures associated with Lennox-Gastaut syndrome, Dravet syndrome and tuberous sclerosis complex. Despite many years of clinical experience, there...…
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  • 5 min
  • This content is machine translated How do weight loss interventions affect the muscles?

Reflective evaluation: do not neglect qualitative aspects

Both in the context of exclusively dietary interventions and after bariatric surgery or treatment with GLP(glucagon-like peptide)-1 analogs, there is not only a reduction in weight, but also a loss...…
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