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Pharmacology and toxicology

246 posts
  • This content is machine translated Biologics for atopic dermatitis

Symptom relief through targeted inhibition of inflammatory signaling pathways

Monoclonal antibodies are systems therapeutics that block specific cytokines or receptors and can thus selectively influence individual activation cascades of the immune system. Both dupilumab and tralokinmab – the two…
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  • 5 min
  • This content is machine translated The difficult acne patient

Systemic retinoid therapy – informing about opportunities and risks

Oral isotretinoin can be very effective in treating severe forms of acne that do not respond sufficiently to topical and systemic antibiotic therapy. In advance, patients should be informed about…
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  • 12 min
  • This content is machine translated Parkinson's disease

Optimization of L-dopa therapy at the onset of effect fluctuations.

Levodopa is still considered the gold standard in the treatment of Parkinson’s disease. Among them, good symptom control with a high quality of life can be achieved for the patient…
CME-Test
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  • 5 min
  • This content is machine translated Non-tumor related chronic pain

Opioid use: new data from mixed-methods analysis

Opioid analgesics are an important drug therapy option for chronic pain, and care must be taken to use them as directed. To gain insight into “real world” care practices of…
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  • 12 min
  • This content is machine translated Parkinson's disease

Optimization of L-dopa therapy at the onset of effect fluctuations

Levodopa is still considered the gold standard in the treatment of Parkinson’s disease. Among them, good symptom control with a high quality of life can be achieved for the patient…
CME-Test
View Post
  • 4 min
  • This content is machine translated Restless legs syndrome: guideline update

Substitute iron deficiency and always use dopaminergics judiciously

The diagnostic criteria for restless legs syndrome (RLS) were revised and agreed upon in a consensus conference. The previous division into primary and secondary forms of RLS has been replaced…
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  • 4 min
  • This content is machine translated Pain therapy with non-opioid analgesics

Benefit-risk assessment and patient education

In Switzerland, paracetamol, non-steroidal anti-inflammatory drugs (NSAIDs) and metamizole are available as non-opioid analgesics. NSAIDs or metamizole should be considered if acetaminophen does not provide adequate pain relief. A differentiated…
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  • 5 min
  • This content is machine translated Functional dyspepsia

Consider phytotherapeutics as a therapeutic option

Functional dyspepsia (FD) is a heterogeneous disorder in terms of both pathophysiology and symptomatology. Accordingly, there is hardly any intervention that is effective for all patients. In the context of…
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  • 13 min
  • This content is machine translated Multiple sclerosis

S1P receptor modulators in RRMS: tailored therapy management

Modulation of S1P receptors is an important and interesting therapeutic target in the treatment management of multiple sclerosis due to their functional multifold. Currently, three S1P receptor modulators are available…
CME-Test
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  • 3 min
  • This content is machine translated Antidepressant monotherapy

Trazodone with innovative galenics achieves rapid and significant response

The antidepressant monotherapy with trazodone achieves an effective response after only one week with a single daily dose starting at 150 mg. The multifunctional antidepressant mechanism of action of the serotonin…
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  • 3 min
  • This content is machine translated Multiple sclerosis

Effective therapy management also protects brain volume

Each year, a person loses about 0.2-0.4% of their brain volume. So far, so normal. In patients with multiple sclerosis, however, this value is about twice as high. This is due…

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